SCHEMBL2472011

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2470757	0.89	PTGS2 (0.56)	PTGS2PTGS1HTTNPC1RAB9A
	SCHEMBL2477859	0.88	HTT (0.55)	PTGS2PTGS1HTTNPC1RAB9A
	SCHEMBL2471844	0.86	NPC1 (0.61)	PTGS2PTGS1GABRA5HTTNPC1
	SCHEMBL2472121	0.86	PTGS2 (0.50)	PTGS2PTGS1HTTNPC1RAB9A
	SCHEMBL2469006	0.84	PTGS2 (0.53)	PTGS2PTGS1HTTNPC1RAB9A
	SCHEMBL2471573	0.83	PTGS2 (0.47)	PTGS2PTGS1HTTNPC1RAB9A
	SCHEMBL2468902	0.83	PTGS1 (0.47)	PTGS2PTGS1GABRA5HTTNPC1
	SCHEMBL2470915	0.83	PTGS2 (0.47)	PTGS2PTGS1GABRA5HTTNPC1
	SCHEMBL2471971	0.82	PTGS2 (0.46)	PTGS2PTGS1HTTNPC1RAB9A
	SCHEMBL2473691	0.82	L3MBTL1 (0.48)	PTGS2PTGS1HTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.