Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054352 | 0.81 | MAPT (0.49) | TSHRMAPTALDH1A1CYP3A4RECQL | |
| SCHEMBL9688049 | 0.81 | MAPT (0.44) | TSHRMAPTALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL348272 | 0.81 | TSHR (0.59) | TSHRMAPTALDH1A1CYP3A4RECQL | |
| SCHEMBL11219818 | 0.81 | TSHR (0.59) | TSHRMAPTALDH1A1CYP3A4RECQL | |
| SCHEMBL30578459 | 0.81 | TSHR (0.59) | TSHRMAPTALDH1A1CYP3A4RECQL | |
| SCHEMBL23524987 | 0.80 | ALDH1A1 (0.51) | TSHRMAPTALDH1A1POLBKMT2A | |
| SCHEMBL6161257 | 0.80 | MAPT (0.48) | TSHRMAPTALDH1A1CYP3A4RECQL | |
| SCHEMBL29760455 | 0.80 | ALDH1A1 (0.51) | TSHRMAPTALDH1A1POLBKMT2A | |
| SCHEMBL11053592 | 0.79 | MAPT (0.47) | TSHRMAPTALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL126467 | 0.79 | MAPT (0.54) | TSHRMAPTALDH1A1CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437123-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | claimed |
| EP-0999823-B2 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2011-10-05 | — | — | EP | claimed |
| EP-1437123-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2007-06-06 | — | — | EP | claimed |
| EP-1437123-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| EP-0999823-B1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-6712861-B2 | CATIONIC DIRECT DYE | L'OREAL S.A. (FR) | 2004-03-30 | — | — | US | claimed |
| US-20030084516-A9 | Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods | L'OREAL S.A. (FR) | 2003-05-08 | — | — | US | claimed |
| US-20030000023-A9 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL S.A. (FR) | 2003-01-02 | — | — | US | claimed |
| US-20020095732-A1 | Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods | KRAVTCHENKO SYLVAIN (FR) | 2002-07-25 | — | — | US | claimed |
| US-20020004956-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | RONDEAU CHRISTINE (FR) | 2002-01-17 | — | — | US | claimed |
| EP-1149575-A1 | Oxidative dyeing composition for keratin fibres comprising 1-(4-aminophenyl)-pyrrolidine and a particular direct dye | L'OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| EP-0999823-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2000-05-17 | — | — | EP | claimed |
| WO-1999020235-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 1999-04-29 | — | — | WO | claimed |
| EP-0480829-B1 | Hair dyeing composition containing anthraquinones | OREAL (FR) | 1994-04-06 | — | — | EP | claimed |
| US-5226924-A | 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM | L'OREAL (FR) | 1993-07-13 | — | — | US | claimed |
| EP-0480829-A1 | Hair dyeing composition containing anthraquinones | L'OREAL (FR) | 1992-04-15 | — | — | EP | claimed |
| US-20230139146-A1 | DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE | L'OREAL (FR) | 2023-05-04 | — | — | US | disclosed |
| CN-105828882-B | Packaging article comprising an envelope and an anhydrous dye composition comprising a direct dye, use thereof and process for dyeing keratin fibres | 莱雅公司 | 2022-09-30 | — | — | CN | disclosed |
| US-4637821-A | HAIR, DYEING | L'OREAL (FR) | 1987-01-20 | — | — | US | disclosed |
| US-4470826-A | HAIR DYES, NITRO DYES, DIRECT DYES | L'OREAL (FR) | 1984-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030000023-A9 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | KRT18, CYB5R3, TUBB6 | TSHR 4611/4885MAPT 834/4885ALDH1A1 640/4885 |
| US-20020095732-A1 | Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods | KRT18, PLOD1, PLOD2 | TSHR 4814/4885MAPT 559/4885ALDH1A1 60/4885 |
| US-20230139146-A1 | DYEING OR LIGHTENING PROCESS USING A HAND-HELD STYLING DEVICE AND A SUBSTRATE | KRT18, TPM3, PRKDC | TSHR 3326/4885MAPT 904/4885ALDH1A1 372/4885 |
| US-20030084516-A9 | Compositions for oxidation dyeing keratinous fibers comprising at least one oxidation precursor, and at least one direct dye, and dyeing methods | KRT18, PLOD1, PLOD2 | TSHR 4814/4885MAPT 559/4885ALDH1A1 60/4885 |
| US-20020004956-A1 | COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME | KRT18, TUBB1, TUBB4B | TSHR 4711/4885MAPT 522/4885ALDH1A1 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.