Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.56 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65315 | 0.87 | SLC29A1 (0.75) | SLC29A1ADORA3TSHRLMNATP53 | |
| SCHEMBL25167729 | 0.86 | SLC29A1 (0.74) | SLC29A1ADORA3TSHRLMNATP53 | |
| SCHEMBL218771 | 0.86 | DNPH1 (0.70) | P2RX3P2RX2ADORA1 | |
| SCHEMBL12813164 | 0.85 | PRMT5 (0.56) | PRMT5WDR77ADORA3ADORA1ADORA2A | |
| SCHEMBL25356221 | 0.83 | P2RX3 (0.79) | P2RX3P2RX2 | |
| SCHEMBL25358180 | 0.82 | P2RX3 (0.81) | P2RX3P2RX2 | |
| SCHEMBL20608780 | 0.82 | SLC29A1 (0.63) | SLC29A1ADORA3TSHRLMNATP53 | |
| SCHEMBL91052 | 0.81 | SLC29A1 (0.58) | SLC29A1ADORA3P2RX3P2RX2ADORA1 | |
| SCHEMBL1228087 | 0.80 | AHCY (0.72) | SLC29A1ADORA3P2RX3P2RX2ADORA1 | |
| SCHEMBL8683061 | 0.79 | ADORA2A (0.57) | SLC29A1ADORA3TSHRADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373793-A1 | METHOD FOR ASSEMBLY OF POLYNUCLEIC ACID SEQUENCES | ITI Scotland Limited (GB) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010070295-A1 | METHOD FOR ASSEMBLY OF POLYNUCLEIC ACID SEQUENCES | ITI SCOTLAND LIMITED (GB) | 2010-06-24 | — | — | WO | disclosed |
| EP-1644500-A2 | POLYCATIONIC COMPOSITIONS FOR CELLULAR DELIVERY OF POLYNUCLEOTIDES | Sirna Therapeutics, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005007854-A2 | POLYCATIONIC COMPOSITIONS FOR CELLULAR DELIVERY OF POLYNUCLEOTIDES | SIRNA THERAPEUTICS, INC. (US) | 2005-01-27 | — | — | WO | disclosed |