SCHEMBL218771

SCHEMBL218771

C=C(C)CCNc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNPH1 O43598 7/20 0.70
P2RX3 P56373 3/20 0.69
P2RX2 Q9UBL9 3/20 0.69
TAS1R3 Q7RTX0 2/20 0.67
TAS1R1 Q7RTX1 2/20 0.67
ADORA1 P30542 3/20 0.65
PRKAB2 O43741 1/20 0.65
TRPM2 O94759 1/20 0.65
LDHA P00338 1/20 0.65
ADRB2 P07550 1/20 0.65
FBP1 P09467 1/20 0.65
SRC P12931 1/20 0.65
P2RY2 P41231 1/20 0.65
P2RY1 P47900 1/20 0.65
PRKAG1 P54619 1/20 0.65
PRKAA2 P54646 1/20 0.65
PDE4D Q08499 1/20 0.65
KCNH2 Q12809 1/20 0.65
PRKAA1 Q13131 1/20 0.65
PDE3A Q14432 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564165 1.00 DNPH1 (0.70) DNPH1P2RX3P2RX2TAS1R3TAS1R1
SCHEMBL25356221 0.93 P2RX3 (0.79) DNPH1P2RX3P2RX2TAS1R3TAS1R1
SCHEMBL25358180 0.93 P2RX3 (0.81) DNPH1P2RX3P2RX2TRPM2SRC
SCHEMBL30150740 0.92 ADORA1 (0.68) DNPH1P2RX3P2RX2TAS1R3TAS1R1
SCHEMBL8780682 0.89 DNPH1 (0.77) DNPH1P2RX3P2RX2TAS1R3TAS1R1
SCHEMBL8780669 0.89 DNPH1 (0.77) DNPH1P2RX3P2RX2TAS1R3TAS1R1
SCHEMBL4820592 0.88 DNPH1 (0.73) DNPH1P2RX3P2RX2TAS1R3TAS1R1
SCHEMBL6707282 0.88 DNPH1 (0.73) DNPH1P2RX3P2RX2TAS1R3TAS1R1
SCHEMBL25286647 0.87 DNPH1 (0.71) DNPH1P2RX3P2RX2TAS1R3TAS1R1
SCHEMBL20705924 0.87 P2RX3 (0.72) DNPH1P2RX3P2RX2TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090203638-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION VDF FUTURECEUTICALS, INC. (US) 2009-08-13 US claimed
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-07-12 US claimed
WO-2005020892-A2 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-03-10 WO claimed
US-12201075-B2 Methods and compositions for axillary shoot micropropagation of Cannabis and related plants JUSHI IP, LLC (US) 2025-01-21 US disclosed
US-20230265444-A1 GENE-EDITING IN CANNABIS PLANT CANOPY GROWTH CORPORATION (CA) 2023-08-24 US disclosed
US-20220110278-A1 METHODS AND COMPOSITIONS FOR AXILLARY SHOOT MICROPROPAGATION OF CANNABIS AND RELATED PLANTS JUSHI IP, LLC 2022-04-14 US disclosed
US-20210277351-A1 METHODS FOR HETEROTROPHICALLY CULTURING EUGLENA IN HYBRID MEDIA NOBLEGEN INC (CA) 2021-09-09 US disclosed
US-8088752-B2 Methods for metabolic modulation VDF FUTURECEUTICALS, INC. (US) 2012-01-03 US disclosed
US-20090208620-A1 Alimentary Compositions and Methods For Metabolic Modulation VDF FUTURECEUTICALS, INC. (US) 2009-08-20 US disclosed
US-20090203638-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION VDF FUTURECEUTICALS, INC. (US) 2009-08-13 US disclosed
US-20070184067-A1 Alimentary compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-08-09 US disclosed
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation VDF FUTURECEUTICALS 2007-07-12 US disclosed
WO-2005020892-A2 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-03-10 WO disclosed
WO-2005016268-A2 ALIMENTARY COMPOSITIONS AND METHODS FOR METABOLIC MODULATION MITOCHROMA RESEARCH, INC. (US) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161582-A1 Pharmaceutical compositions and methods for metabolic modulation GPR119, PRKAG2, PRKAG1 DNPH1 3996/4885P2RX3 287/4885P2RX2 193/4885
US-20090203638-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR METABOLIC MODULATION GPR119, PRKAG2, GCKR DNPH1 3917/4885P2RX3 247/4885P2RX2 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.