Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65315 | 0.84 | SLC29A1 (0.75) | ADORA2AADORA3ADORA1SLC29A1TSHR | |
| SCHEMBL29405896 | 0.84 | SLC29A1 (0.75) | ADORA2AADORA3ADORA1SLC29A1TSHR | |
| SCHEMBL25167729 | 0.83 | SLC29A1 (0.74) | ADORA2AADORA3ADORA1SLC29A1TSHR | |
| SCHEMBL2472334 | 0.79 | SLC29A1 (0.58) | ADORA2AADORA3ADORA1SLC29A1TSHR | |
| SCHEMBL218771 | 0.78 | DNPH1 (0.70) | ADORA1 | |
| SCHEMBL29564165 | 0.78 | DNPH1 (0.70) | ADORA1 | |
| SCHEMBL30150740 | 0.77 | ADORA1 (0.68) | ADORA1SLC29A1 | |
| SCHEMBL20608780 | 0.76 | SLC29A1 (0.63) | ADORA2AADORA3ADORA1SLC29A1TSHR | |
| SCHEMBL25356221 | 0.75 | P2RX3 (0.79) | — | |
| SCHEMBL28861515 | 0.75 | AHCY (0.78) | ADORA2AADORA3ADORA2BADORA1SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107574157-A | Compositions and methods comprising histidyl-trna synthetase splice variants having non-canonical biological activities | 盘古生物制药有限公司 | 2018-01-12 | — | — | CN | disclosed |
| WO-1998054315-A1 | CELL GROWTH-CONTROLLING OLIGONUCLEOTIDES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-12-03 | — | — | WO | disclosed |