SCHEMBL24723461

SCHEMBL24723461

COc1cccc2[nH]cc(CC(=O)N(C(C)C)C(C)C)c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.55
MTNR1B P49286 1/20 0.55
HTR6 P50406 1/20 0.54
HTR2A P28223 5/20 0.53
SCN5A Q14524 1/20 0.44
SCN2A Q99250 1/20 0.44
ADRB2 P07550 1/20 0.43
HTR2C P28335 2/20 0.43
HTR2B P41595 2/20 0.43
GAA P10253 2/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HTR1A P08908 1/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
THRB P10828 1/20 0.43
DNMT1 P26358 1/20 0.43
RECQL P46063 1/20 0.43
CASP6 P55212 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29993190 0.86 HTR6 (0.61) MTNR1AMTNR1BHTR6HTR2ASCN5A
SCHEMBL24723312 0.86 HTR6 (0.61) MTNR1AMTNR1BHTR6HTR2ASCN5A
SCHEMBL25139745 0.84 MTNR1A (0.60) MTNR1AMTNR1BHTR6HTR2ASCN5A
SCHEMBL24723315 0.84 MTNR1A (0.56) MTNR1AMTNR1BHTR6HTR2ASCN5A
SCHEMBL29992722 0.82 MTNR1A (0.55) MTNR1AMTNR1BHTR6HTR2ASCN5A
SCHEMBL6770793 0.81 KDM4E (0.64) MTNR1AMTNR1BHTR6HTR2ASCN5A
SCHEMBL24814487 0.81 MTNR1A (0.66) MTNR1AMTNR1BHTR6HTR2ASCN5A
SCHEMBL24723412 0.80 MEN1 (0.58) MTNR1AMTNR1BHTR6HTR2ASCN5A
SCHEMBL24723333 0.79 CDK4 (0.57) MTNR1AMTNR1BHTR6HTR2AKDM4E
SCHEMBL29992742 0.78 HTR6 (0.51) MTNR1AMTNR1BHTR6HTR2ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254081-A1 CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS KARE CHEMICAL TECHNOLOGIES INC. (CA) 2024-08-01 US disclosed
CN-117597329-A Method for the catalytic synthesis of tryptamine and precursors thereof 凯尔化学科技公司 2024-02-23 CN disclosed
WO-2022232931-A1 CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS KARE CHEMICAL TECHNOLOGIES INC. (CA) 2022-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254081-A1 CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS HNMT, TPSB2, TPSG1 MTNR1A 263/4885MTNR1B 394/4885HTR6 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.