Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151025 | 0.86 | ACMSD (0.50) | ACMSDAKR1C2AKR1C1FOLH1NPC1 | |
| SCHEMBL4342150 | 0.85 | ALDH1A1 (0.52) | ACMSDAKR1C2AKR1C1ALDH1A1ALOX15 | |
| SCHEMBL139845 | 0.81 | ALDH1A1 (0.59) | FOLH1NPC1RAB9AALDH1A1ALOX15 | |
| SCHEMBL30047867 | 0.81 | ALDH1A1 (0.59) | FOLH1NPC1RAB9AALDH1A1ALOX15 | |
| SCHEMBL17796931 | 0.80 | ALDH1A1 (0.48) | ACMSDAKR1C2AKR1C1FOLH1NPC1 | |
| SCHEMBL3416936 | 0.78 | SLC6A3 (0.62) | AKR1C2AKR1C1ALDH1A1ALOX15HNF4A | |
| SCHEMBL24723508 | 0.77 | ALDH1A1 (0.48) | AKR1C2AKR1C1ALDH1A1KMT2AAKR1C3 | |
| SCHEMBL17796995 | 0.77 | ACMSD (0.53) | ACMSDAKR1C2AKR1C1DHODHALDH1A1 | |
| SCHEMBL2312006 | 0.76 | LTB4R2 (0.55) | ACMSDAKR1C2AKR1C1FOLH1NPC1 | |
| SCHEMBL15917362 | 0.75 | FEN1 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544400-B2 | Bimesogenic compounds and flexoelectric devices | MERCK PATENT GMBH (DE) | 2009-06-09 | — | — | US | disclosed |
| US-20080142758-A1 | Bimesogenic Compounds And Flexoelectric Devices | MERCK PATENT GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
| EP-1828345-B1 | BIMESOGENIC COMPOUNDS AND FLEXOELECTRIC DEVICES | MERCK PATENT GMBH (DE) | 2008-05-14 | — | — | EP | disclosed |
| EP-1828345-A1 | BIMESOGENIC COMPOUNDS AND FLEXOELECTRIC DEVICES | Merck Patent GmbH (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066688-A1 | BIMESOGENIC COMPOUNDS AND FLEXOELECTRIC DEVICES | MERCK PATENT GMBH (DE) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080142758-A1 | Bimesogenic Compounds And Flexoelectric Devices | MLX, FOXM1, SFXN1 | ACMSD 2475/4885AKR1C2 3378/4885AKR1C1 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.