Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | ICMT | O60725 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494963 | 0.90 | HTR6 (0.57) | MTNR1AMTNR1BNQO2ICMTHTR6 | |
| SCHEMBL2685182 | 0.83 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2HTR6ADRB2 | |
| SCHEMBL2686296 | 0.82 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2HTR6ADRB2 | |
| SCHEMBL13888101 | 0.81 | ADRB2 (0.70) | MTNR1AMTNR1BNQO2HTR6ADRB2 | |
| SCHEMBL29993260 | 0.81 | AKR1C3 (0.58) | MTNR1AICMTHTR6AKR1C3AKR1C2 | |
| SCHEMBL24723269 | 0.77 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2HTR6ADRB2 | |
| SCHEMBL12185393 | 0.76 | ADRB2 (0.76) | MTNR1AMTNR1BNQO2HTR6ADRB2 | |
| SCHEMBL18509701 | 0.75 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2HTR6ADRB2 | |
| SCHEMBL7388695 | 0.75 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2HTR6ADRB2 | |
| SCHEMBL15242222 | 0.74 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2HTR6ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232931-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | KARE CHEMICAL TECHNOLOGIES INC. (CA) | 2022-11-10 | — | — | WO | disclosed |