Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.32 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933040 | 0.82 | LMNA (0.42) | HRH4CNR2CTSKIDH1 | |
| SCHEMBL8039831 | 0.81 | APP (0.51) | TPH1HRH4APPIDH1IDH2 | |
| SCHEMBL24724746 | 0.78 | CNR2 (0.37) | TPH1HRH4CNR2IDH1CNR1 | |
| SCHEMBL8053409 | 0.78 | APP (0.51) | TPH1HRH4APPIDH1RET | |
| SCHEMBL25868870 | 0.77 | VCP (0.44) | TPH1CNR2EPHX1 | |
| SCHEMBL24724733 | 0.75 | ALDH1A1 (0.46) | TPH1CNR2 | |
| SCHEMBL23346071 | 0.75 | HDAC6 (0.40) | TPH1CNR2IDH1CNR1IDH2 | |
| SCHEMBL4829259 | 0.73 | GALR1 (0.58) | CNR2IDH1CNR1 | |
| SCHEMBL8054361 | 0.72 | IDH1 (0.46) | TPH1APPIDH1IDH2RET | |
| SCHEMBL22188708 | 0.71 | HRH4 (0.45) | HRH4CTSKIDH2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |