Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | TPH1 | P17752 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | AOC1 | P19801 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039831 | 0.96 | APP (0.51) | APPTPH1HRH4CA2NOS3 | |
| SCHEMBL8054361 | 0.86 | IDH1 (0.46) | APPTPH1CA2IDH1AOC1 | |
| SCHEMBL29167207 | 0.81 | KCNH3 (0.54) | APPTPH1HRH4PTGS2JAK2 | |
| SCHEMBL28062315 | 0.81 | TPH1 (0.65) | APPTPH1IDH1ADORA2AADORA1 | |
| SCHEMBL24724734 | 0.78 | TPH1 (0.39) | APPTPH1HRH4IDH1RET | |
| SCHEMBL20511448 | 0.77 | PDE4A (0.42) | APPTPH1CA2IDH1AOC1 | |
| SCHEMBL14504385 | 0.75 | MEN1 (0.54) | HRH4MEN1KMT2A | |
| SCHEMBL23169265 | 0.74 | AOC1 (0.42) | APPTPH1CA2IDH1AOC1 | |
| SCHEMBL23175076 | 0.73 | HRH4 (0.57) | HRH4KCNH2HRH3 | |
| SCHEMBL5382326 | 0.73 | HRH4 (0.37) | APPTPH1HRH4CA2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130332-A | USING A GROUP 8 METAL CATALYST AND ALDEHYDES OR KETONE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0760369-A1 | PROCESS FOR ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-05 | — | — | EP | disclosed |