SCHEMBL822098

SCHEMBL822098

Cc1cccc(C(F)(F)c2cccc(C)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.52
PTPN5 P54829 1/20 0.46
KIF11 P52732 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
KCNH2 Q12809 1/20 0.43
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HTT P42858 2/20 0.41
CYP1A2 P05177 1/20 0.41
MAPT P10636 1/20 0.41
NFE2L2 Q16236 1/20 0.41
MEN1 O00255 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
KCNK3 O14649 1/20 0.40
KCNK9 Q9NPC2 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2631997 0.93 KIF11 (0.47) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL822102 0.91 NFE2L2 (0.44) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL12792016 0.89 ACHE (0.42) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL148048 0.85 NFE2L2 (0.55) ACHEPTPN5KIF11MAPK1ALDH1A1
SCHEMBL20118959 0.83 KIF11 (0.44) KIF11CYP3A4CYP1A2MAPTMEN1
Bromide SCHEMBL27462091 0.83 NFE2L2 (0.53) ACHEPTPN5KIF11MAPK1ALDH1A1
Ammonia Solution, Strong SCHEMBL1869257 0.83 NFE2L2 (0.53) ACHEPTPN5KIF11MAPK1ALDH1A1
SCHEMBL8242617 0.83 ACHE (0.50) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL18891585 0.83 ACHE (0.50) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL15255849 0.81 ACHE (0.48) ACHEPTPN5KIF11CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-20230357505-A1 POLY(AMIDE-IMIDE) COPOLYMER, METHOD OF MANUFACTURING THE SAME, POLY(AMIDE-IMIDE) COPOLYMER FILM, WINDOW FOR DISPLAY DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-09 US disclosed
US-20230312813-A1 METHOD FOR PRODUCING ANION EXCHANGE RESIN AND METHOD FOR PRODUCING ELECTROLYTE MEMBRANE UNIVERSITY OF YAMANASHI (JP) 2023-10-05 US disclosed
US-11739183-B2 Poly(amide-imide) copolymer, method of manufacturing the same, poly(amide-imide) copolymer film, window for display device, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-29 US disclosed
EP-3086316-B1 SOUND ABSORBING AND INSULATING MATERIAL AND METHOD FOR MANUFACTURING THE SAME HYUNDAI MOTOR CO LTD (KR) 2019-07-31 EP disclosed
US-9975997-B2 Compositions, composites prepared therefrom, and films and electronic devices including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-22 US disclosed
US-9805707-B2 Sound absorbing and insulating material and method for manufacturing the same HYUNDAI MOTOR COMPANY (KR) 2017-10-31 US disclosed
US-9805707-B2 Sound absorbing and insulating material and method for manufacturing the same HYUNDAI MOTOR COMPANY (KR) 2017-10-31 US disclosed
US-20170267821-A1 POLYIMIDE FILMS AND PRODUCTION METHODS THEREOF SAMSUNG ELECTRONICS CO LTD (KR) 2017-09-21 US disclosed
US-20170267821-A1 POLYIMIDE FILMS AND PRODUCTION METHODS THEREOF SAMSUNG ELECTRONICS CO LTD (KR) 2017-09-21 US disclosed
US-20110009506-A1 PREPARATION METHOD OF POLYBENZOXAZOLES BY THERMAL REARRANGEMENT, POLYBENZOXAZOLES PREPARED THEREBY, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2011-01-13 US disclosed
US-20100292356-A1 PREPARATION METHOD OF POLYBENZIMIDAZOLE IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2010-11-18 US disclosed
US-20100099804-A1 POLYMER COMPOUNDS AND A PREPARATION METHOD THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2010-04-22 US disclosed
WO-2010041909-A2 POLYMER AND PREPARATION METHOD THEREOF 한양대학교 산학협력단 (KR) 2010-04-15 WO disclosed
US-20090297850-A1 HOLLOW FIBER, DOPE COMPOSITION FOR FORMING HOLLOW FIBER, AND METHOD OF MAKING HOLLOW FIBER USING THE SAME IUCF-HYU(INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2009-12-03 US disclosed
US-20090286078-A1 POLYIMIDES DOPE COMPOSITION, PREPARATION METHOD OF HOLLOW FIBER USING THE SAME AND HOLLOW FIBER PREPARED THEREFROM INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-11-19 US disclosed
US-20090286904-A1 POLYAMIC ACIDS DOPE COMPOSITION, PREPARATION METHOD OF HOLLOW FIBER USING THE SAME AND HOLLOW FIBER PREPARED THEREFROM INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-11-19 US disclosed
US-20090282982-A1 HOLLOW FIBER, DOPE COMPOSITION FOR FORMING HOLLOW FIBER, AND METHOD OF PREPARING HOLLOW FIBER USING THE SAME IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2009-11-19 US disclosed
WO-2009113747-A1 PREPARATION METHOD OF POLYBENZOXAZOLES BY THERMAL REARRANGEMENT, POLYBENZOXAZOLES PREPARED THEREBY, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-17 WO disclosed
WO-2009107889-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312813-A1 METHOD FOR PRODUCING ANION EXCHANGE RESIN AND METHOD FOR PRODUCING ELECTROLYTE MEMBRANE SLC9A5, SLC9A1, SLC9A2 ACHE 4640/4885PTPN5 4722/4885KIF11 3786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.