Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20663205 | 0.83 | DHODH (0.47) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| SCHEMBL6245212 | 0.82 | CYP3A4 (0.64) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| SCHEMBL21131297 | 0.80 | CYP3A4 (0.62) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| SCHEMBL8292092 | 0.80 | CYP3A4 (0.62) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| SCHEMBL25455975 | 0.78 | CYP3A4 (0.38) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| SCHEMBL9419533 | 0.78 | CYP3A4 (0.55) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| SCHEMBL4581102 | 0.77 | CYP3A4 (0.58) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| SCHEMBL21239231 | 0.76 | LMNA (0.41) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| Amitraz SCHEMBL9026554 | 0.76 | CYP3A4 (0.83) | CYP3A4ADRA2AALDH1A1KDM4ELMNA | |
| SCHEMBL22366968 | 0.75 | CYP3A4 (0.56) | CYP3A4ADRA2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960016-A | Preparation method of N-methyl-bis (2, 4-xylyliminomethyl) amine | 常州齐晖药业有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-115960016-A | Preparation method of N-methyl-bis (2, 4-xylyliminomethyl) amine | 常州齐晖药业有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115960016-A | Preparation method of N-methyl-bis (2, 4-xylyliminomethyl) amine | 常州齐晖药业有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115960016-A | Preparation method of N-methyl-bis (2, 4-xylyliminomethyl) amine | 常州齐晖药业有限公司 | 2023-04-14 | — | — | CN | disclosed |
| EP-2550962-B1 | Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2019-10-30 | — | — | EP | disclosed |
| CN-104397013-A | Efficient insecticide containing cyphenothrin, amitraz and transfluthrin | QINGDAO SHINAN DISTR LONGDE TRADITIONAL CHINESE MEDICINE INST | 2015-03-11 | — | — | CN | disclosed |
| CN-104336054-A | Efficient cyphenothrin, amitraz and bensulide-containing insecticide | QINGDAO KANGHE FOOD CO LTD | 2015-02-11 | — | — | CN | disclosed |
| CN-104273162-A | Efficient insecticide containing chlorfenvinphos, cyphenothrin and amitraz | Qingdao yongtong elevator engineering co ltd | 2015-01-14 | — | — | CN | disclosed |
| CN-104273160-A | High-efficiency insecticide containing flonicamid, cyphenothrin and amitraz | QINGDAO RUNXIN WEIYE SCIENCE & TRADING CO LTD | 2015-01-14 | — | — | CN | disclosed |
| EP-2550962-A2 | Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof | Merial Limited (US) | 2013-01-30 | — | — | EP | disclosed |
| EP-2364147-A2 | COMPOSITIONS COMPRISING 1-ARYLPYRAZOLE ALONE OR IN COMBINATION WITH FORMAMIDINE FOR THE TREATMENT OF PARASITIC INFECTION | Merial Limited (US) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010059529-A2 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2010-05-27 | — | — | WO | disclosed |
| CN-1237054-C | Insecticidal and acaricidal agents | AGERO KANSHO CO LTD (JP) | 2006-01-18 | — | — | CN | disclosed |
| US-20030191171-A1 | Pyrazolyl compound | AGRO-KANESHO CO., LTD. (JP) | 2003-10-09 | — | — | US | disclosed |
| CN-1399515-A | Insecticidal and acaricidal agents | AGERO KANSHO CO LTD (JP) | 2003-02-26 | — | — | CN | disclosed |
| CN-1176960-A | Novel ester compounds, pesticidal compositions containing same and intermediates for synthesis thereof | SUMITOMO CHEMICAL CO (JP) | 1998-03-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191171-A1 | Pyrazolyl compound | GSTO1, CBR3, GSTM1 | CYP3A4 206/4885ADRA2A 1658/4885ALDH1A1 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.