Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20731005 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2LIMK1IKBKB | |
| SCHEMBL23938107 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4ESMN1; SMN2LIMK1IKBKB | |
| SCHEMBL23937997 | 0.78 | KDM4E (0.41) | ALDH1A1KDM4ESMN1; SMN2LIMK1IKBKB | |
| SCHEMBL19737518 | 0.74 | MAPT (0.56) | ALDH1A1KDM4ESMN1; SMN2LIMK1NPC1 | |
| SCHEMBL23317016 | 0.71 | LIMK1 (0.56) | LIMK1IKBKBNPC1MAPTNOS3 | |
| SCHEMBL21703985 | 0.71 | LIMK1 (0.34) | ALDH1A1KDM4ESMN1; SMN2LIMK1IKBKB | |
| SCHEMBL18537683 | 0.70 | LIMK1 (0.67) | ALDH1A1KDM4ESMN1; SMN2LIMK1NPC1 | |
| SCHEMBL20731564 | 0.68 | USP25 (0.38) | — | |
| SCHEMBL23938014 | 0.68 | LIMK1 (0.33) | ALDH1A1KDM4ESMN1; SMN2LIMK1IKBKB | |
| SCHEMBL20731982 | 0.68 | ALDH1A1 (0.62) | ALDH1A1KDM4ESMN1; SMN2LIMK1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | USP28, USP25, USP24 | ALDH1A1 2167/4885KDM4E 403/4885SMN1; SMN2 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.