Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127075 | 0.87 | KDM4E (0.31) | METAP2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL27543159 | 0.79 | TYR (0.40) | ALOX5METAP2TYRKDM4EALDH1A1 | |
| SCHEMBL6076307 | 0.75 | EIF4A1 (0.35) | ALOX5KDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL2820985 | 0.70 | MMP13 (0.34) | KDM4ECYP4F2CYP4A11ALDH1A1LMNA | |
| SCHEMBL8134178 | 0.70 | HTT (0.39) | KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6077824 | 0.69 | ALOX5 (0.36) | ALOX5KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6078666 | 0.69 | ALOX5 (0.36) | ALOX5KDM4ECYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL6077311 | 0.68 | ALOX5 (0.36) | ALOX5KDM4EHPGD | |
| SCHEMBL6076169 | 0.67 | ALOX5 (0.34) | ALOX5KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL5833263 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011110583-A2 | FUNGICIDAL MIXTURES COMPRISING TRIAZOLE DERIVATIVES | BASF SE (DE) | 2011-09-15 | — | — | WO | claimed |
| US-11912684-B2 | N-(4-pyridyl)nicotinamide compound or salt thereof | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2024-02-27 | — | — | US | disclosed |
| EP-3617196-B1 | N-(4-PYRIDYL) NICOTINAMIDE COMPOUND OR SALT THEREOF | ISHIHARA SANGYO KAISHA (JP) | 2023-06-07 | — | — | EP | disclosed |
| US-20210115015-A1 | N-(4-PYRIDYL)NICOTINAMIDE COMPOUND OR SALT THEREOF | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2021-04-22 | — | — | US | disclosed |
| EP-3617196-A1 | N-(4-PYRIDYL) NICOTINAMIDE COMPOUND OR SALT THEREOF | Ishihara Sangyo Kaisha, Ltd. (JP) | 2020-03-04 | — | — | EP | disclosed |
| WO-2011110583-A2 | FUNGICIDAL MIXTURES COMPRISING TRIAZOLE DERIVATIVES | BASF SE (DE) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115015-A1 | N-(4-PYRIDYL)NICOTINAMIDE COMPOUND OR SALT THEREOF | NAMPT, NAPRT, NNT | ALOX5 1143/4885PPARG 2458/4885PPARA 1280/4885 |
| US-11912684-B2 | N-(4-pyridyl)nicotinamide compound or salt thereof | NAMPT, NAPRT, NNT | ALOX5 1143/4885PPARG 2458/4885PPARA 1280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.