Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077824 | 0.88 | ALOX5 (0.36) | ALOX5HTTNPC1HPGDMAPK1 | |
| SCHEMBL6076307 | 0.87 | EIF4A1 (0.35) | ALOX5EIF4A1HTTNPC1HPGD | |
| SCHEMBL6077311 | 0.86 | ALOX5 (0.36) | ALOX5HTTNPC1HPGDMAPK1 | |
| SCHEMBL6078666 | 0.85 | ALOX5 (0.36) | ALOX5HTTNPC1HPGDMAPK1 | |
| SCHEMBL6077713 | 0.85 | ALOX5 (0.44) | ALOX5HPGDMAPK1LMNAKDM4E | |
| SCHEMBL6076793 | 0.85 | ALOX5 (0.40) | ALOX5HTTHPGDLMNAKDM4E | |
| SCHEMBL6076615 | 0.84 | ALOX5 (0.33) | ALOX5HTTNPC1HPGDMAPK1 | |
| SCHEMBL6076165 | 0.77 | DHODH (0.32) | HTTMAPK1NPSR1LMNAKDM4E | |
| SCHEMBL6077005 | 0.75 | DHODH (0.43) | ALOX5LMNAALDH1A1 | |
| SCHEMBL845559 | 0.71 | HTT (0.46) | ALOX5HTTNPC1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067668-B2 | 4-quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-0990648-B1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-6680282-B2 | FUNGICIDE HAVING AN EXCELLENT CONTROL EFFECT; 4-QUINOLINOL DERIVATIVES HAVING SPECIFIC SUBSTITUENT AT 1,2 AND ATLEAST ONE SUBSTITUENT AT 5,6,7,8 POSITION | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-20 | — | — | US | disclosed |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-0990648-A1 | 4-QUINOLINOL DERIVATIVES AND AGROHORTICULTURAL BACTERICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | Meiji Seika Kaisha, Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152728-A1 | 4-Quinolinol derivatives and fungicides containing the same as an active ingredient used for agriculture and horticulture | CYP51A1, CYP4X1, CYP4Z1 | ALOX5 2069/4885EIF4A1 1012/4885AKR1C2 532/4885 |
| US-20030119863-A1 | 4-Quinolinol derivatives and agrohorticultural bactericides containing the same as active ingredient | CYP51A1, DDT, PGLS | ALOX5 2036/4885EIF4A1 1618/4885AKR1C2 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.