Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28281546 | 0.80 | LMNA (0.44) | SPHK1LMNAMAPTDNM1TSHR | |
| SCHEMBL1412474 | 0.79 | LCK (0.44) | MAPTCA2TP53CYP1A2CYP3A4 | |
| SCHEMBL28281612 | 0.75 | TSHR (0.46) | LMNADNM1TSHRSMN1; SMN2CA2 | |
| SCHEMBL27494877 | 0.75 | LCK (0.48) | MAPTTSHRSMN1; SMN2CA2GPR84 | |
| SCHEMBL28742173 | 0.75 | LCK (0.48) | MAPTTSHRSMN1; SMN2CA2GPR84 | |
| SCHEMBL6577529 | 0.75 | LCK (0.48) | MAPTTSHRSMN1; SMN2CA2GPR84 | |
| SCHEMBL27493668 | 0.75 | LCK (0.48) | MAPTTSHRSMN1; SMN2CA2GPR84 | |
| SCHEMBL27565023 | 0.75 | LCK (0.48) | MAPTTSHRSMN1; SMN2CA2GPR84 | |
| SCHEMBL2441613 | 0.74 | LMNA (0.38) | SPHK1LMNAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL7568238 | 0.74 | LMNA (0.38) | SPHK1LMNAMAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530193-B2 | Kinase inhibitors | THE UNIVERSITY OF MANCHESTER (GB) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530193-B2 | Kinase inhibitors | CAMKK2, CAMK1, CAMKK1 | SPHK1 601/4885LMNA 4006/4885MAPT 2893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.