SCHEMBL24738564

SCHEMBL24738564

Cc1ccccc1-c1ccc2c(c1)c1cc(-c3ccccc3C)ccc1n2-c1cncc(-n2c3ccc(-c4ccccc4C)cc3c3cc(-c4ccccc4C)ccc32)c1-c1cccc(C#N)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
ADRA2C P18825 1/20 0.37
BRD4 O60885 1/20 0.36
KIT P10721 1/20 0.36
AR P10275 1/20 0.36
CYP1A2 P05177 4/20 0.36
CYP3A4 P08684 4/20 0.36
CYP2D6 P10635 3/20 0.36
CYP2C19 P33261 3/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
USP7 Q93009 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA3 P34903 2/20 0.36
IRAK4 Q9NWZ3 1/20 0.36
IDO1 P14902 1/20 0.36
PIM1 P11309 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21929227 0.97 PTGER4 (0.36) CYP11B1CYP11B2ADRA2CBRD4KIT
SCHEMBL24738563 0.93 CYP11B1 (0.37) CYP11B1CYP11B2ADRA2CBRD4AR
SCHEMBL21929226 0.92 CYP11B1 (0.35) CYP11B1CYP11B2ADRA2CBRD4AR
SCHEMBL21929268 0.91 CYP11B2 (0.41) CYP11B1CYP11B2ARCYP1A2CYP3A4
SCHEMBL21928548 0.91 GRIN1 (0.34) CYP11B1CYP11B2ADRA2CBRD4KIT
SCHEMBL22761061 0.90 ADRA2C (0.39) ADRA2CBRD4KITARCYP1A2
SCHEMBL24737201 0.89 CYP1A2 (0.38) CYP11B1CYP11B2KITCYP1A2CYP3A4
SCHEMBL21929030 0.88 PTGER4 (0.39) CYP11B1CYP11B2AR
SCHEMBL21928373 0.88 CYP1A2 (0.36) CYP11B1CYP11B2KITCYP1A2CYP3A4
SCHEMBL21929205 0.88 NR3C1 (0.40) ADRA2CCYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220388960-A1 ORGANIC MOLECULES FOR USE IN LIGHT-EMITTING DEVICES CYNORA GMBH (DE) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388960-A1 ORGANIC MOLECULES FOR USE IN LIGHT-EMITTING DEVICES ALDH1A2, AOX1, CYBA CYP11B1 432/4885CYP11B2 163/4885ADRA2C 2751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.