SCHEMBL24739645

SCHEMBL24739645

CO[Si](CCNC(=O)c1cccc(-c2cccc(Oc3cc4c5c(cc(Oc6cccc(-c7cccc(C(=O)NCC[Si](OC)(OC)OC)c7)c6)c6c7c(Oc8cccc(-c9cccc(C(=O)NCC[Si](OC)(OC)OC)c9)c8)cc8c9c(cc(Oc%10cccc(-c%11cccc(C(=O)NCC[Si](OC)(OC)OC)c%11)c%10)c(c3c56)c97)C(=O)N(C(C(=O)NC3CCCCC3)C(C)C)C8=O)C(=O)N(C(C(=O)NC3CCCCC3)C(C)C)C4=O)c2)c1)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
ERN1 O75460 1/20 0.39
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HPGD P15428 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
PKM P14618 1/20 0.37
ROCK2 O75116 3/20 0.36
FAAH O00519 1/20 0.36
TRPA1 O75762 1/20 0.36
EPHX2 P34913 1/20 0.36
FAAH2 Q6GMR7 1/20 0.36
MGLL Q99685 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24705016 0.82 CTSK (0.39) MAPTSMN1; SMN2TP53LMNA
SCHEMBL24908947 0.80 LMNA (0.45) RAB9AKMT2AMAPTHPGDALDH1A1
SCHEMBL24739617 0.74 ROCK2 (0.38) RAB9ASMN1; SMN2HPGDALDH1A1ROCK2
SCHEMBL24704922 0.74 FFAR1 (0.34) KMT2AMAPTTHRBTP53LMNA
SCHEMBL24705325 0.70 PTPN1 (0.30) KMT2A
SCHEMBL24705463 0.70 CTSS (0.42) CTSLCTSS
SCHEMBL24739686 0.69 SMN1; SMN2 (0.32) KMT2AMEN1SMN1; SMN2TP53TSHR
SCHEMBL24739620 0.68 PDE4A (0.33) RAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL24739634 0.68 CTSK (0.35) MAPTTP53BRD4LMNACTSL
SCHEMBL24739613 0.68 SMN1; SMN2 (0.36) KMT2AMEN1SMN1; SMN2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220390841-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2022-12-08 US disclosed