SCHEMBL2473980

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2473792	0.94	ALDH1A1 (0.54)	ALDH1A1MAPTHSD17B10TSHROPRM1
	SCHEMBL2476586	0.93	HSD17B10 (0.55)	ALDH1A1MAPTHSD17B10TSHROPRM1
	SCHEMBL2477106	0.90	OPRM1 (0.54)	ALDH1A1MAPTHSD17B10TSHROPRM1
	SCHEMBL2477227	0.90	OPRM1 (0.52)	ALDH1A1MAPTHSD17B10TSHROPRM1
	SCHEMBL4219720	0.90	ALDH1A1 (0.51)	ALDH1A1MAPTHSD17B10TSHROPRM1
	SCHEMBL2474354	0.89	MAPT (0.57)	ALDH1A1MAPTHSD17B10TSHROPRM1
	SCHEMBL2478140	0.89	HSD17B10 (0.52)	ALDH1A1MAPTHSD17B10TSHROPRM1
	SCHEMBL2475895	0.89	MCHR1 (0.55)	ALDH1A1MAPTHSD17B10TSHROPRM1
	SCHEMBL3835327	0.89	ALDH1A1 (0.50)	ALDH1A1MAPTHSD17B10TSHROPRM1
	SCHEMBL2474808	0.88	ALDH1A1 (0.54)	ALDH1A1MAPTHSD17B10TSHRHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.