Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.58 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24740852 | 0.86 | ALOX15 (0.60) | ALOX15LMNAPOLBMAPTNUDT1 | |
| SCHEMBL24019964 | 0.81 | ALOX15 (0.58) | ALOX15EIF4A3LMNAPOLBMAPT | |
| SCHEMBL25768433 | 0.81 | ALOX15 (0.53) | ALOX15NUDT1DRD2DRD3HRH4 | |
| SCHEMBL25812182 | 0.80 | ALOX15 (0.52) | ALOX15NUDT1HRH4 | |
| SCHEMBL30310723 | 0.79 | XDH (0.47) | ALOX15EIF4A3MAPTCDK1CCNB1 | |
| SCHEMBL7673791 | 0.79 | XDH (0.47) | ALOX15EIF4A3MAPTCDK1CCNB1 | |
| SCHEMBL25812177 | 0.78 | ALOX15 (0.51) | ALOX15NUDT1HRH4 | |
| SCHEMBL4041607 | 0.78 | CDK1 (0.61) | ALOX15EIF4A3LMNAPOLBMAPT | |
| SCHEMBL30310477 | 0.78 | EIF4A3 (0.61) | EIF4A3LMNAMAPT | |
| SCHEMBL7677228 | 0.78 | EIF4A3 (0.61) | EIF4A3LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524940-B1 | Inhibitors of cysteine proteases and methods of use thereof | Pardes Biosciences, Inc. (US) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11524940-B1 | Inhibitors of cysteine proteases and methods of use thereof | CTRL, CTSV, CTSL | ALOX15 1749/4885EIF4A3 608/4885LMNA 2486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.