Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9659113 | 1.00 | TP53 (0.50) | TP53OPRM1CA1SPHK1NR1I2 | |
| Potassium Ion SCHEMBL8585180 | 1.00 | TP53 (0.50) | TP53OPRM1CA1SPHK1NR1I2 | |
| SCHEMBL3924982 | 0.96 | TP53 (0.50) | TP53OPRM1CA1SPHK1NR1I2 | |
| SCHEMBL27503908 | 0.96 | TP53 (0.50) | TP53OPRM1CA1SPHK1NR1I2 | |
| SCHEMBL7629661 | 0.96 | TP53 (0.50) | TP53OPRM1CA1SPHK1NR1I2 | |
| SCHEMBL9019654 | 0.96 | TP53 (0.50) | TP53OPRM1CA1SPHK1NR1I2 | |
| SCHEMBL6691126 | 0.96 | TP53 (0.50) | TP53OPRM1CA1SPHK1NR1I2 | |
| SCHEMBL8677767 | 0.93 | TP53 (0.52) | TP53OPRM1CA1SPHK1NR1I2 | |
| SCHEMBL27767212 | 0.86 | TP53 (0.43) | TP53OPRM1CA1NR1I2RECQL | |
| SCHEMBL29178075 | 0.85 | FAAH (0.46) | TP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111691217-B | Method for recovering free starch in papermaking white water | 瑞辰星生物技术（广州）有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-111691224-B | Modified starch and preparation method and application thereof | 瑞辰星生物技术（广州）有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-111691223-B | Process for making paper | 瑞辰星生物技术（广州）有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-111691217-A | Method for recovering free starch in papermaking white water | 瑞辰星生物技术（广州）有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-111691224-A | Modified starch and preparation method and application thereof | 瑞辰星生物技术（广州）有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-111691223-A | Method for making paper | 瑞辰星生物技术（广州）有限公司 | 2020-09-22 | — | — | CN | disclosed |
| EP-2370527-B1 | ADDITIVES FOR ENHANCING THE ANTISTATIC PROPERTIES OF CONDUCTIVE POLYMER-BASED COATINGS | ESSILOR INT (FR) | 2012-10-24 | — | — | EP | disclosed |
| US-20110248223-A1 | Additives for Enhancing the Antistatic Properties of Conductive Polymer-Based Coatings | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2011-10-13 | — | — | US | disclosed |
| EP-2370527-A1 | ADDITIVES FOR ENHANCING THE ANTISTATIC PROPERTIES OF CONDUCTIVE POLYMER-BASED COATINGS | Essilor International (Compagnie Générale D'Optique) (FR) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010076314-A1 | ADDITIVES FOR ENHANCING THE ANTISTATIC PROPERTIES OF CONDUCTIVE POLYMER-BASED COATINGS | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2010-07-08 | — | — | WO | disclosed |