Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 4/20 | 0.41 |
| ▸ | BCR | P11274 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24742760 | 0.95 | L3MBTL1 (0.48) | L3MBTL1PARP14PARP10CA12CA1 | |
| SCHEMBL24742765 | 0.87 | DDB1 (0.47) | ALDH1A1USP30TSHRITGB3ITGA2B | |
| SCHEMBL24742759 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL24743004 | 0.81 | ITGB3 (0.41) | LMNAHPGDTSHRITGB3ITGA2B | |
| SCHEMBL24743245 | 0.80 | MAPT (0.46) | L3MBTL1PARP14PARP10CA12CA1 | |
| SCHEMBL22355671 | 0.79 | ITGB3 (0.37) | ITGB3ITGA2B | |
| SCHEMBL24742998 | 0.79 | TSHR (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23529077 | 0.77 | ROCK2 (0.57) | — | |
| SCHEMBL24743008 | 0.77 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL24743010 | 0.75 | ITGB3 (0.44) | HPGDITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704121-B1 | DIAZASPIRO ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-12-21 | — | — | EP | disclosed |