Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.37 |
| ▸ | LIPE | Q05469 | 7/20 | 0.37 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22355757 | 0.86 | ITGB3 (0.41) | ITGB3ITGA2B | |
| SCHEMBL22355673 | 0.86 | ITGB3 (0.38) | ITGB3ITGA2BLIPE | |
| SCHEMBL22355681 | 0.83 | PPIB (0.37) | ITGB3ITGA2B | |
| SCHEMBL22355669 | 0.83 | OPRM1 (0.32) | ITGB3ITGA2BLIPE | |
| SCHEMBL22355668 | 0.83 | ROCK2 (0.42) | LIPEOTUD7B | |
| SCHEMBL24742760 | 0.80 | L3MBTL1 (0.48) | ITGB3ITGA2B | |
| SCHEMBL21490362 | 0.80 | ROCK2 (0.44) | LIPEOTUD7B | |
| SCHEMBL29443020 | 0.80 | ROCK2 (0.44) | LIPEOTUD7B | |
| SCHEMBL22355670 | 0.79 | OTUD7B (0.32) | OTUD7B | |
| SCHEMBL24743239 | 0.79 | L3MBTL1 (0.44) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481817-B1 | SPIROLACTAMS AS INHIBITORS OF ROCK | BRISTOL MYERS SQUIBB CO (US) | 2020-08-19 | — | — | EP | disclosed |