Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 11/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973104 | 0.85 | LMNA (0.56) | LMNAPOLBATMDHODHKLKB1 | |
| SCHEMBL973238 | 0.84 | ATM (0.47) | ATMDHODHEGFR | |
| SCHEMBL974151 | 0.82 | CYP1A2 (0.51) | POLBATMSMN1; SMN2 | |
| SCHEMBL971566 | 0.82 | POLB (0.66) | LMNAPOLBATMTRPV1SMN1; SMN2 | |
| SCHEMBL973770 | 0.81 | LMNA (0.62) | LMNAPOLBDHODHSMN1; SMN2EGFR | |
| SCHEMBL972255 | 0.80 | EGFR (0.48) | DHODHSMN1; SMN2EGFR | |
| SCHEMBL973052 | 0.78 | ATM (0.69) | LMNAPOLBATMSMN1; SMN2 | |
| SCHEMBL31475430 | 0.78 | ATM (0.69) | LMNAATM | |
| SCHEMBL973185 | 0.78 | ATM (0.69) | LMNAATM | |
| SCHEMBL11962938 | 0.77 | LMNA (0.45) | LMNAPOLBATMDHODHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257530-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| EP-2093216-A1 | Process for preparing substituted biphenylanilides | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |