SCHEMBL2474656

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2500319	0.92	OPRM1 (0.50)	OPRM1OPRD1NAMPTTSHRMAPT
	SCHEMBL2475852	0.91	OPRM1 (0.53)	OPRM1OPRD1NAMPTTSHRMAPT
	SCHEMBL2473469	0.90	HDAC1 (0.61)	OPRM1OPRD1NAMPTTSHRHDAC1
	SCHEMBL2477227	0.90	OPRM1 (0.52)	OPRM1OPRD1NAMPTTSHRMAPT
	SCHEMBL2477106	0.90	OPRM1 (0.54)	OPRM1OPRD1NAMPTTSHRMAPT
	SCHEMBL4229195	0.89	USP2 (0.51)	OPRM1OPRD1NAMPTTSHRMAPT
	SCHEMBL2470965	0.88	OPRM1 (0.53)	OPRM1OPRD1NAMPTTSHRMAPT
	SCHEMBL2478739	0.88	OPRM1 (0.55)	OPRM1OPRD1NAMPTTSHRMAPT
	SCHEMBL2476477	0.88	USP2 (0.54)	OPRM1OPRD1NAMPTTSHRMAPT
	SCHEMBL2476922	0.88	OPRM1 (0.52)	OPRM1OPRD1NAMPTTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.