SCHEMBL2476477

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2476317	0.93	TSHR (0.53)	USP2ROCK2HDAC1ALDH1A1GAA
	SCHEMBL2478739	0.93	OPRM1 (0.55)	USP2ROCK2HDAC1TSHROPRM1
	SCHEMBL2473883	0.92	TSHR (0.57)	USP2ROCK2HDAC1ALDH1A1GAA
	SCHEMBL2477106	0.91	OPRM1 (0.54)	USP2HDAC1ALDH1A1TSHROPRM1
	SCHEMBL2475852	0.91	OPRM1 (0.53)	USP2HDAC1TSHROPRM1OPRD1
	SCHEMBL2474773	0.90	USP2 (0.50)	USP2ROCK2HDAC1ALDH1A1GAA
	SCHEMBL2477252	0.90	TSHR (0.64)	USP2ROCK2HDAC1ALDH1A1GAA
	SCHEMBL2470965	0.90	OPRM1 (0.53)	USP2HDAC1ALDH1A1TSHROPRM1
	SCHEMBL2473469	0.90	HDAC1 (0.61)	USP2HDAC1TSHROPRM1OPRD1
	SCHEMBL2477227	0.90	OPRM1 (0.52)	HDAC1ALDH1A1TSHROPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.