Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673211 | 0.84 | MEN1 (0.49) | MEN1KMT2APTPN1CA12CA1 | |
| Terephthalic Acid SCHEMBL27585525 | 0.83 | MEN1 (0.42) | MEN1KMT2APTPN1CA12CA1 | |
| Terephthalic Acid SCHEMBL27475251 | 0.83 | MEN1 (0.42) | MEN1KMT2APTPN1CA12CA1 | |
| Benzoic Acid SCHEMBL28206140 | 0.82 | DAO (0.42) | MEN1KMT2ACA12CA1CA2 | |
| Bicarbonate SCHEMBL27933722 | 0.79 | TSHR (0.36) | MEN1KMT2ACA1CA2ALDH1A1 | |
| Oxalic Acid SCHEMBL27401043 | 0.78 | CYP2C19 (0.35) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL8916545 | 0.78 | MEN1 (0.33) | MEN1KMT2ACA1CA2MCL1 | |
| Methoxymethane SCHEMBL28149002 | 0.77 | CYP2D6 (0.40) | — | |
| SCHEMBL5372908 | 0.77 | MEN1 (0.63) | MEN1KMT2APTPN1CA12CA1 | |
| Acetic Acid SCHEMBL663243 | 0.76 | CYP2C19 (0.40) | MEN1KMT2ACA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112089714-A | Oxazolidinone-quinolone hybrid antibacterial agents for the parenteral treatment or prophylaxis of bacterial diseases | 莫弗凯姆有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-105246476-A | Combination therapy comprising oxazolidinone-quinolones for use in treating bacterial infections | MORPHOCHEM AG KOMB CHEMIE | 2016-01-13 | — | — | CN | disclosed |
| CN-102333749-B | Production of substituted phenylene aromatic diesters | DOW GLOBAL TECHNOLOGIES INC | 2015-04-22 | — | — | CN | disclosed |
| US-8604235-B2 | Production of substituted phenylene aromatic diesters and compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| US-8507717-B2 | Production of substituted phenylene aromatic diesters | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| CN-102333749-A | Production of substituted phenylene aromatic diesters | DOW GLOBAL TECHNOLOGIES INC (US) | 2012-01-25 | — | — | CN | disclosed |
| EP-2376423-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| EP-2373604-A2 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2011-10-12 | — | — | EP | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
| WO-2010078519-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010078512-A2 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20100174105-A1 | Production of Substituted Phenylene Aromatic Diesters | W.R. GRACE & CO.-CONN. | 2010-07-08 | — | — | US | disclosed |
| CN-100544719-C | Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections | MORPHOCHEM AG (DE) | 2009-09-30 | — | — | CN | disclosed |
| CN-101432003-A | Non-cardiotoxic pharmaceutical compounds | BARBEAU DONALD L (US) | 2009-05-13 | — | — | CN | disclosed |
| CN-1832746-A | Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections | MORPHOCHEM AG KOMB CHEMIE (DE) | 2006-09-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174105-A1 | Production of Substituted Phenylene Aromatic Diesters | DDT, COMT, DDC | MEN1 3581/4885KMT2A 735/4885PTPN1 2777/4885 |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | PAH, DDC, DDT | MEN1 3036/4885KMT2A 1611/4885PTPN1 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.