Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24754231 | 0.81 | IDO1 (0.40) | KMT2AIDO1DRD2TBXA2RMEN1 | |
| SCHEMBL24754228 | 0.81 | KMT2A (0.39) | KMT2AIDO1DRD2TBXA2RTDO2 | |
| SCHEMBL24754234 | 0.80 | CYP1A2 (0.40) | KMT2AIDO1DRD2TBXA2RTDO2 | |
| SCHEMBL4182991 | 0.75 | CYP19A1 (0.48) | KMT2AIDO1MEN1ALDH1A1HPGD | |
| SCHEMBL24754590 | 0.75 | IDO1 (0.40) | KMT2AIDO1DRD2TBXA2RTDO2 | |
| SCHEMBL23516966 | 0.74 | ALDH1A1 (0.50) | DRD2TBXA2RALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL27551879 | 0.74 | HTT (0.54) | KMT2AIDO1MEN1TDO2ALDH1A1 | |
| SCHEMBL27477655 | 0.74 | KDM4E (0.53) | IDO1ALDH1A1HPGD | |
| SCHEMBL27501601 | 0.74 | NPBWR1 (0.56) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24754238 | 0.73 | TDP1 (0.59) | KMT2ADRD2TBXA2RMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022263829-A1 | COMPOUNDS AND THEIR USE FOR THE TREATMENT OF α1-ANTITRYPSIN DEFICIENCY | Z Factor Limited (GB) | 2022-12-22 | — | — | WO | disclosed |