SCHEMBL2475739

SCHEMBL2475739

CCC(C)(C)C1=CC(=Cc2ccccc2)C=C(C(C)(C)CC)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
NPC1 O15118 2/20 0.41
ATM Q13315 2/20 0.41
GPR35 Q9HC97 1/20 0.41
MAPT P10636 4/20 0.38
NPSR1 Q6W5P4 3/20 0.38
MEN1 O00255 3/20 0.38
MAPK1 P28482 2/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MDM2 Q00987 1/20 0.38
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
CYP1A2 P05177 3/20 0.37
CYP24A1 Q07973 1/20 0.35
F3 P13726 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL86407 0.83 ATM (0.56) KMT2ANPC1ATMGPR35MAPT
Hno SCHEMBL6475533 0.80 ATM (0.54) KMT2ANPC1ATMGPR35MAPT
Benzoquinone SCHEMBL28737726 0.77 ATM (0.51) KMT2ANPC1ATMGPR35MAPT
Benzoquinone SCHEMBL23209758 0.76 KMT2A (0.50) KMT2ANPC1ATMGPR35MAPT
SCHEMBL11678515 0.76 CYP1A2 (0.42) KMT2ANPC1ATMGPR35CYP1A2
SCHEMBL24118938 0.76 NPC1 (0.41) KMT2ANPC1ATMGPR35SMN1; SMN2
SCHEMBL24236846 0.76 KMT2A (0.41) KMT2ANPC1ATMGPR35MAPT
SCHEMBL38660251 0.74 ATM (0.55) KMT2ANPC1ATMGPR35MAPT
SCHEMBL4455979 0.73 POLB (0.30)
SCHEMBL19730332 0.73 KMT2A (0.66) KMT2ANPC1ATMGPR35MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1379584-B1 FLAME RETARDANT COMPOSITIONS CIBA SC HOLDING AG (CH) 2005-08-24 EP claimed
US-20040097619-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-05-20 US claimed
US-5670692-A 7-substituted quinone methides as inhibitors for unsaturated monomers CIBA-GEIGY CORPORATION (US) 1997-09-23 US claimed
US-8187346-B2 Stabilization of pygas for storage FINA TECHNOLOGY, INC. (US) 2012-05-29 US disclosed
EP-2370552-A1 STABILIZATION OF PYGAS FOR STORAGE Fina Technology, Inc. (US) 2011-10-05 EP disclosed
WO-2010078096-A1 STABILIZATION OF PYGAS FOR STORAGE FINA TECHNOLOGY, INC. (US) 2010-07-08 WO disclosed
US-20100162617-A1 Stabilization of Pygas for Storage FINA TECHNOLOGY, INC. (US) 2010-07-01 US disclosed
US-7473795-B2 Blends of quinone alkide and nitroxyl compounds as polymerization inhibitors UNIROYAL CHEMICAL COMPANY, INC. (US) 2009-01-06 US disclosed
US-7470734-B2 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-12-30 US disclosed
US-20060155140-A1 Blends of quinone alkide and nitroxyl compounds as polymerization inhibitors UNIROYAL CHEMICAL COMPANY, INC A CORPORATION OF THE STATE OF DELAWARE 2006-07-13 US disclosed
US-7045647-B2 Blends of quinone alkide and nitroxyl compounds and polymerization inhibitors UNIROYAL CHEMICAL COMPANY, INC. (US) 2006-05-16 US disclosed
EP-0737660-B1 Inhibition of unsaturated monomers with 7-aryl quinone methides ONDEO NALCO ENERGY SERV LP (US) 2002-08-14 EP disclosed
WO-2002033026-A1 BLENDS OF QUINONE ALKIDE AND NITROXYL COMPOUNDS AS POLYMERIZATION INHIBITORS UNIROYAL CHEMICAL COMPANY, INC. (US) 2002-04-25 WO disclosed
EP-0737659-B1 7-Substituted quinone methides as inhibitors for unsaturated monomers CIBA SC HOLDING AG (CH) 2000-07-05 EP disclosed
US-5750765-A 7-substituted quinone methides as inhibitors for unsaturated monomers CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-05-12 US disclosed
US-5670692-A 7-substituted quinone methides as inhibitors for unsaturated monomers CIBA-GEIGY CORPORATION (US) 1997-09-23 US disclosed
US-5616774-A POLYMERIZATION INHIBITION DURING THE DISTILLATION AND PURIFICATION PROCESS OF AROMATIC VINYL OR ACRYLIC COMPOUNDS CIBA-GEIGY CORPORATION (US) 1997-04-01 US disclosed
US-5583247-A PREMATURE POLYMERIZATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1996-12-10 US disclosed
EP-0737659-A1 7-Substituted quinone methides as inhibitors for unsaturated monomers CIBA-GEIGY AG (CH) 1996-10-16 EP disclosed
EP-0737660-A1 Inhibition of unsaturated monomers with 7-aryl quinone methides CIBA-GEIGY AG (CH) 1996-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100162617-A1 Stabilization of Pygas for Storage PYGL, PYGB, PYGM KMT2A 404/4885NPC1 4861/4885ATM 2482/4885
US-20060155140-A1 Blends of quinone alkide and nitroxyl compounds as polymerization inhibitors SQOR, NQO1, NQO2 KMT2A 2450/4885NPC1 3524/4885ATM 2227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.