Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | MMP2 | P08253 | 3/20 | 0.62 |
| ▸ | MMP9 | P14780 | 3/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.62 |
| ▸ | MMP13 | P45452 | 2/20 | 0.62 |
| ▸ | MMP3 | P08254 | 1/20 | 0.62 |
| ▸ | MMP7 | P09237 | 1/20 | 0.62 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261912 | 0.86 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 | |
| SCHEMBL570839 | 0.85 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 | |
| SCHEMBL19450297 | 0.84 | MMP2 (0.56) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 | |
| SCHEMBL18498935 | 0.84 | IDO1 (0.56) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 | |
| SCHEMBL8131965 | 0.84 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 | |
| SCHEMBL28677877 | 0.83 | KDM4E (0.71) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 | |
| SCHEMBL7383813 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 | |
| SCHEMBL24762900 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 | |
| SCHEMBL24762895 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 | |
| SCHEMBL3239227 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2GAAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190821-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES INC (US) | 2024-06-13 | — | — | US | disclosed |
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190821-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF | PACSIN2, TPX2, PRSS12 | ALDH1A1 3608/4885SMN1; SMN2 523/4885GAA 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.