Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24762050 | 0.79 | LMNA (0.41) | ALDH1A1LMNASMN1; SMN2NPC1HPGD | |
| SCHEMBL24762180 | 0.73 | PKM (0.51) | ALDH1A1LMNASMN1; SMN2NPC1MEN1 | |
| SCHEMBL24763412 | 0.69 | LMNA (0.39) | ALDH1A1LMNASMN1; SMN2NPC1HPGD | |
| SCHEMBL9461363 | 0.68 | GRIN1 (0.69) | SLC6A4GRIN2DGRIN3BCYP2B6SLC6A2 | |
| SCHEMBL332623 | 0.68 | MAOA (0.63) | ALDH1A1LMNASMN1; SMN2NPC1HPGD | |
| Cyclohexane SCHEMBL28084543 | 0.66 | MAOA (0.57) | ALDH1A1LMNASMN1; SMN2NPC1HPGD | |
| SCHEMBL28084553 | 0.66 | MAOA (0.61) | ALDH1A1LMNASMN1; SMN2NPC1HPGD | |
| SCHEMBL510481 | 0.66 | MAOA (0.53) | ALDH1A1LTA4HMAOAMAOBMEN1 | |
| SCHEMBL16111935 | 0.65 | SIGMAR1 (0.62) | LMNASLC6A4GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL31713446 | 0.65 | MAOA (0.45) | ALDH1A1LMNASMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |