SCHEMBL2476986

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8000226	0.93	KDM4E (0.47)	KDM4EALDH1A1HPGDUSP2TSHR
	SCHEMBL3230728	0.90	KDM4E (0.46)	KDM4EALDH1A1HPGDUSP2TSHR
	SCHEMBL3232454	0.88	KDM4E (0.44)	KDM4EALDH1A1HPGDUSP2TSHR
	SCHEMBL3225579	0.87	KDM4E (0.43)	KDM4EALDH1A1HPGDUSP2TSHR
	SCHEMBL2477790	0.86	HSD17B10 (0.49)	KDM4EALDH1A1TSHRHSD17B10KDM1A
	SCHEMBL3831123	0.86	HDAC1 (0.50)	KDM4EALDH1A1HPGDUSP2TSHR
	SCHEMBL2478129	0.86	HDAC1 (0.50)	KDM4EALDH1A1TSHRNPSR1GAA
	SCHEMBL2475683	0.86	HDAC1 (0.54)	KDM4EALDH1A1HPGDTSHRHSD17B10
	SCHEMBL2479082	0.86	OPRM1 (0.51)	KDM4EALDH1A1HPGDUSP2TSHR
	SCHEMBL4396390	0.85	OPRM1 (0.50)	KDM4EALDH1A1USP2TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.