SCHEMBL2477252

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2476477	0.90	USP2 (0.54)	TSHRHDAC1HDAC2ALDH1A1KDM4E
	SCHEMBL2477705	0.90	HDAC1 (0.57)	TSHRHDAC1HDAC2ALDH1A1KDM4E
	SCHEMBL2473883	0.90	TSHR (0.57)	TSHRHDAC1ALDH1A1LMNAMAPT
	SCHEMBL2476317	0.89	TSHR (0.53)	TSHRHDAC1ALDH1A1KDM4ELMNA
	SCHEMBL2478739	0.89	OPRM1 (0.55)	TSHRHDAC1HDAC2MAPTHDAC3
	SCHEMBL2473939	0.88	TSHR (0.60)	TSHRHDAC1ALDH1A1KDM4ELMNA
	SCHEMBL4224529	0.88	TSHR (0.60)	TSHRHDAC1HDAC2ALDH1A1KDM4E
	SCHEMBL2476586	0.88	HSD17B10 (0.55)	TSHRHDAC1HDAC2ALDH1A1KDM4E
	SCHEMBL2477106	0.88	OPRM1 (0.54)	TSHRHDAC1HDAC2ALDH1A1KDM4E
	SCHEMBL2475852	0.88	OPRM1 (0.53)	TSHRHDAC1HDAC2MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.