SCHEMBL2476969

SCHEMBL2476969

c1ccc(-c2nnc[nH]2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.50
LMNA P02545 5/20 0.50
METAP1 P53582 4/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
NPC1 O15118 9/20 0.48
RAB9A P51151 8/20 0.48
SMN1; SMN2 Q16637 7/20 0.48
TP53 P04637 4/20 0.48
PKM P14618 4/20 0.48
ALOX15 P16050 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
HSD17B10 Q99714 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30403779 1.00 KDM4E (0.50) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL16125563 0.88 KDM4E (0.60) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL12075543 0.77 MEN1 (0.36) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5478697 0.74 KDM4E (0.59) KDM4ELMNAMETAP1CCR1CCR5
Dipyridyl SCHEMBL4150988 0.72 KDM4E (0.93) KDM4ELMNAMETAP1CCR1CCR5
Dipyridyl SCHEMBL1884115 0.72 KDM4E (0.93) KDM4ELMNAMETAP1CCR1CCR5
Dipyridyl SCHEMBL16026844 0.72 KDM4E (0.93) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL24001509 0.71 GABRA1 (0.31)
SCHEMBL2491046 0.70 MTOR (0.45) KDM4ECYP1A2POLBNPC1RAB9A
Dipyridyl SCHEMBL3711450 0.69 KDM4E (1.00) KDM4ELMNAMETAP1CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085579-B N hexyl carbazole substituted-phenyl benzothiazole iridium (III) complexs and its preparation 太原理工大学 2018-03-27 CN claimed
EP-2542562-A1 LUMINESCENT ORGANOMETALLIC COMPOUND Technische Universität Braunschweig (DE) 2013-01-09 EP claimed
US-8278238-B2 Triplet emitter having condensed five-membered rings Universitaet Bruanschweig (DE) 2012-10-02 US claimed
WO-2011107491-A1 LUMINESCENT ORGANOMETALLIC COMPOUND TECHNISCHE UNIVERSITÄT BRAUNSCHWEIG (DE) 2011-09-09 WO claimed
US-20090165846-A1 TRIPLET EMITTER HAVING CONDENSED FIVE-MEMBERED RINGS UNIVERSITAET BRAUNSCHWEIG (DE) 2009-07-02 US claimed
CN-101300264-A Triplet emitter having condensed five-membered rings UNIV BRAUNSCHWEIG TECH (DE) 2008-11-05 CN claimed
EP-1926741-A1 TRIPLET EMITTER HAVING CONDENSED FIVE-MEMBERED RINGS Technische Universität Braunschweig (DE) 2008-06-04 EP claimed
WO-2007028822-A1 TRIPLET EMITTER HAVING CONDENSED FIVE-MEMBERED RINGS TECHNISCHE UNIVERSITÄT BRAUNSCHWEIG (DE) 2007-03-15 WO claimed
WO-2007028417-A1 TRIPLETT EMITTER HAVING CONDENSED FIVE-MEMBERED RINGS TECHNISCHE UNIVERSITÄT BRAUNSCHWEIG (DE) 2007-03-15 WO claimed
EP-4692940-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELECTRONIC DEVICE, AND ELECTRONIC DEVICE MANUFACTURING METHOD Sumitomo Bakelite Co., Ltd. (JP) 2026-02-11 EP disclosed
US-20250136574-A1 SELECTIVE AGENTS TARGETING MYCOBACTERIUM TUBERCULOSIS UNIV MISSISSIPPI (US) 2025-05-01 US disclosed
EP-4472630-A2 SELECTIVE AGENTS TARGETING MYCOBACTERIUM TUBERCULOSIS University of Mississippi (US) 2024-12-11 EP disclosed
WO-2023147571-A2 SELECTIVE AGENTS TARGETING MYCOBACTERIUM TUBERCULOSIS UNIVERSITY OF MISSISSIPPI (US) 2023-08-03 WO disclosed
CN-115698855-A Photosensitive resin composition 住友电木株式会社 2023-02-03 CN disclosed
EP-1883687-A1 LIGHT EMITTING COMPOUND FOR ELECTROLUMINESCENT APPLICATIONS Technische Universität Braunschweig (DE) 2008-02-06 EP disclosed
CN-101018796-A Metal complex, light-emitting solid, organic EL element, and organic EL display FUJI FILM CORP (JP) 2007-08-15 CN disclosed
WO-2007028822-A1 TRIPLET EMITTER HAVING CONDENSED FIVE-MEMBERED RINGS TECHNISCHE UNIVERSITÄT BRAUNSCHWEIG (DE) 2007-03-15 WO disclosed
WO-2007028417-A1 TRIPLETT EMITTER HAVING CONDENSED FIVE-MEMBERED RINGS TECHNISCHE UNIVERSITÄT BRAUNSCHWEIG (DE) 2007-03-15 WO disclosed
WO-2006119800-A1 LIGHT EMITTING COMPOUND FOR ELECTROLUMINESCENT APPLICATIONS TECHNISCHE UNIVERSITÄT BRAUNSCHWEIG (DE) 2006-11-16 WO disclosed
EP-0127847-A1 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives HOECHST UK LIMITED (GB) 1984-12-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090165846-A1 TRIPLET EMITTER HAVING CONDENSED FIVE-MEMBERED RINGS MT-ND5, MCM5, PIN4 KDM4E 2352/4885LMNA 4521/4885METAP1 4075/4885
US-20250136574-A1 SELECTIVE AGENTS TARGETING MYCOBACTERIUM TUBERCULOSIS SLC11A2, FNTB, ABCC1 KDM4E 3606/4885LMNA 3706/4885METAP1 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.