Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.74 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.67 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.67 |
| ▸ | SMO | Q99835 | 1/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337488 | 0.92 | KCNK9 (0.81) | RAB9ANPC1NLRP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL14808084 | 0.90 | ALDH1A1 (0.70) | RAB9ANPC1NLRP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL5713551 | 0.89 | NPC1 (0.73) | RAB9ANPC1ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL1337468 | 0.88 | KCNK9 (0.80) | RAB9ANPC1NLRP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL1336791 | 0.88 | KCNK3 (0.73) | RAB9ANPC1NLRP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11167290 | 0.88 | EPHX1 (0.77) | RAB9ANPC1ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL2351338 | 0.87 | RAB9A (0.65) | RAB9ANPC1NLRP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL3059348 | 0.87 | RAB9A (0.77) | RAB9ANPC1ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL12129902 | 0.87 | MEN1 (0.81) | RAB9ANPC1NLRP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL1337469 | 0.87 | TRPV1 (0.72) | RAB9ANPC1NLRP3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | PTGER1, PTGIS, PTGIR | RAB9A 1059/4885NPC1 174/4885NLRP3 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.