SCHEMBL2477133

SCHEMBL2477133

CC1(C(=O)O)C2C=CC(C2)C1C1C2CC3CC(C2)CC1C3

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.40
ALDH1A1 P00352 2/20 0.40
POLB P06746 2/20 0.40
CTDSP1 Q9GZU7 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 3/20 0.38
LMNA P02545 2/20 0.38
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6468952 0.90 ALDH1A1 (0.37) TDP1ALDH1A1POLBCTDSP1MEN1
SCHEMBL17948249 0.81 MEN1 (0.30) TDP1ALDH1A1POLBCTDSP1MEN1
SCHEMBL2476476 0.78 ALDH1A1 (0.32) TDP1ALDH1A1POLBCTDSP1MEN1
SCHEMBL4733433 0.77
SCHEMBL10388139 0.74 TDP1 (0.41) TDP1ALDH1A1POLBCTDSP1MEN1
SCHEMBL6764223 0.72 MAPK1 (0.32) EPHX2
SCHEMBL717502 0.72
SCHEMBL5076356 0.70 TDP1 (0.56) TDP1ALDH1A1POLBCTDSP1MEN1
SCHEMBL1062711 0.70 TDP1 (0.56) TDP1ALDH1A1POLBCTDSP1MEN1
SCHEMBL17652072 0.70 TDP1 (0.56) TDP1ALDH1A1POLBCTDSP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130095425-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-18 US disclosed
EP-1078945-B1 Polymer for use in a photoresist composition SAMSUNG ELECTRONICS CO LTD (KR) 2011-10-12 EP disclosed
US-6642336-B1 Ultraviolet radiation transparent; improved adhesion, contrast and dry etch resistance SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-11-04 US disclosed
EP-1078945-A2 Polymer for use in a photoresist composition SAMSUNG ELECTRONICS CO. LTD. (KR) 2001-02-28 EP disclosed