Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24774281 | 0.83 | PTGS2 (0.39) | KDM4EDYRK1BDYRK1ADYRK2ROCK1 | |
| SCHEMBL24773657 | 0.80 | KMO (0.38) | DYRK1BDYRK1ADYRK2BPTFMAPK10 | |
| SCHEMBL24774090 | 0.77 | DYRK1A (0.35) | KDM4EL3MBTL1DYRK1BDYRK1ADYRK2 | |
| SCHEMBL24774092 | 0.75 | BPTF (0.37) | KDM4EDYRK1BDYRK1ADYRK2LMNA | |
| SCHEMBL1490042 | 0.74 | MTOR (0.37) | KDM4EDYRK1BDYRK1ADYRK2ROCK1 | |
| SCHEMBL6840084 | 0.74 | KDM4B (0.46) | KDM4ELMNAPOLBMAPTRAB9A | |
| SCHEMBL4447801 | 0.72 | BPTF (0.54) | KDM4EL3MBTL1PTGS2LMNAPOLB | |
| SCHEMBL28146826 | 0.72 | NPC1 (0.45) | KDM4EDYRK1BDYRK1ADYRK2PTGS2 | |
| SCHEMBL5361055 | 0.71 | KDM4E (0.52) | KDM4EALOX15L3MBTL1PTGS2LMNA | |
| SCHEMBL30122726 | 0.71 | SDHB (0.47) | KDM4ELMNAPOLBBPTFMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253033-A1 | CHEMICAL COUPLING LINKER AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-12-08 | — | — | WO | disclosed |