SCHEMBL24786368

SCHEMBL24786368

CCCCNC(=O)C(CCSSC(=O)c1ccccc1)NC(=O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ NAAA Q02083 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ CRHBP P24387 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ CRHR2 Q13324 1/20 0.47
▸ GRIN1 Q05586 2/20 0.45
▸ GRIN2A Q12879 2/20 0.45
▸ LMNA P02545 1/20 0.44
▸ PAX8 Q06710 1/20 0.44
▸ NPC1 O15118 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ CTSL P07711 1/20 0.43
▸ CTSB P07858 1/20 0.43
▸ CTSS P25774 1/20 0.43
▸ CTSK P43235 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24786352 0.90 L3MBTL1 (0.49) L3MBTL1NAAAGRIN1GRIN2ALMNA
SCHEMBL14279162 0.82 L3MBTL1 (0.53) L3MBTL1NAAAGRIN1GRIN2ANPC1
SCHEMBL14279160 0.78 NAAA (0.60) L3MBTL1NAAAMEN1ALDH1A1KMT2A
SCHEMBL2250363 0.77 L3MBTL1 (0.62) L3MBTL1LMNANPC1RAB9A
SCHEMBL506059 0.76 NAAA (0.65) L3MBTL1NAAAMEN1ALDH1A1KMT2A
SCHEMBL506060 0.76 NAAA (0.65) L3MBTL1NAAAMEN1ALDH1A1KMT2A
SCHEMBL10543883 0.74 GRIA1 (0.71) L3MBTL1CTSLCTSSCTSK
SCHEMBL10543878 0.74 GRIA1 (0.71) L3MBTL1CTSLCTSSCTSK
SCHEMBL2244204 0.74 L3MBTL1 (0.61) L3MBTL1NPC1RAB9A
SCHEMBL6184058 0.73 CTSL (0.68) CTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220401554-A1 USE OF MEMBRANE INHIBITORS TO ENHANCE VACCINE DEVELOPMENT AGAINST ENVELOPED VIRUSES CORNELL UNIVERSITY 2022-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220401554-A1 USE OF MEMBRANE INHIBITORS TO ENHANCE VACCINE DEVELOPMENT AGAINST ENVELOPED VIRUSES PIGS, VMA21, FURIN L3MBTL1 4157/4885NAAA 428/4885MEN1 1126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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