SCHEMBL24786352

SCHEMBL24786352

CCCCNC(=O)C(CSSC(=O)c1ccccc1)NC(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ NAAA Q02083 1/20 0.48
▸ LMNA P02545 1/20 0.44
▸ PAX8 Q06710 1/20 0.44
▸ GRIN1 Q05586 2/20 0.44
▸ GRIN2A Q12879 2/20 0.44
▸ CTSL P07711 4/20 0.44
▸ CTSS P25774 2/20 0.44
▸ CTSK P43235 2/20 0.44
▸ CTSB P07858 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ GRIA1 P42261 1/20 0.43
▸ TSHR P16473 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ HDAC3 O15379 1/20 0.42
▸ HDAC4 P56524 1/20 0.42
▸ HDAC1 Q13547 1/20 0.42
▸ HDAC7 Q8WUI4 1/20 0.42
▸ HDAC2 Q92769 1/20 0.42
▸ HDAC10 Q969S8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24786368 0.90 L3MBTL1 (0.48) L3MBTL1NAAALMNAPAX8GRIN1
SCHEMBL14279162 0.78 L3MBTL1 (0.53) L3MBTL1NAAAGRIN1GRIN2ACTSL
SCHEMBL9915089 0.78 GAA (0.48) L3MBTL1LMNACTSL
SCHEMBL506060 0.77 NAAA (0.65) L3MBTL1NAAAGRIA1HDAC3
SCHEMBL506059 0.77 NAAA (0.65) L3MBTL1NAAAGRIA1HDAC3
SCHEMBL10543883 0.75 GRIA1 (0.71) L3MBTL1CTSLCTSSCTSKGRIA1
SCHEMBL10543878 0.75 GRIA1 (0.71) L3MBTL1CTSLCTSSCTSKGRIA1
SCHEMBL7793390 0.75 KMT2A (0.57) L3MBTL1GRIN1GRIN2ACTSLCTSS
SCHEMBL14279160 0.74 NAAA (0.60) L3MBTL1NAAAGRIN1GRIN2AGRIA1
SCHEMBL10073683 0.73 CTSL (0.49) CTSLCTSSCTSKCTSBHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220401554-A1 USE OF MEMBRANE INHIBITORS TO ENHANCE VACCINE DEVELOPMENT AGAINST ENVELOPED VIRUSES CORNELL UNIVERSITY 2022-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220401554-A1 USE OF MEMBRANE INHIBITORS TO ENHANCE VACCINE DEVELOPMENT AGAINST ENVELOPED VIRUSES PIGS, VMA21, FURIN L3MBTL1 4157/4885NAAA 428/4885LMNA 414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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