Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25625115 | 0.76 | AKT1 (0.36) | IKZF1DRD2 | |
| SCHEMBL24891511 | 0.75 | HTR6 (0.32) | — | |
| SCHEMBL24789370 | 0.75 | TLR9 (0.33) | — | |
| SCHEMBL25619901 | 0.73 | IKZF1 (0.35) | IKZF1DRD2 | |
| SCHEMBL24790875 | 0.73 | PRKAA2 (0.35) | CHRM4 | |
| SCHEMBL25626791 | 0.72 | DRD2 (0.42) | IKZF1DRD2 | |
| SCHEMBL24791516 | 0.71 | XIAP (0.37) | DRD2 | |
| SCHEMBL24790237 | 0.71 | HRH3 (0.37) | DRD2 | |
| SCHEMBL25616346 | 0.70 | IKZF1 (0.37) | IKZF1DRD2 | |
| SCHEMBL24790272 | 0.70 | IKZF1 (0.35) | IKZF1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672949-B1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2022-12-21 | — | — | EP | disclosed |