Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF1 | Q13422 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25625115 | 0.88 | AKT1 (0.36) | IKZF1DRD2MEN1KMT2ACCR5 | |
| SCHEMBL24790875 | 0.85 | PRKAA2 (0.35) | ACHE | |
| SCHEMBL24790325 | 0.83 | DRD2 (0.39) | DRD2DRD4DRD3CCR5 | |
| SCHEMBL24790924 | 0.80 | KDM4E (0.38) | CXCR4DRD4KMT2ACCR5PARP1 | |
| SCHEMBL20936104 | 0.80 | — | — | |
| SCHEMBL24790272 | 0.80 | IKZF1 (0.35) | IKZF1DRD2 | |
| SCHEMBL24791545 | 0.79 | IKZF2 (0.38) | IKZF1DRD2 | |
| SCHEMBL24790866 | 0.79 | DRD2 (0.39) | DRD2ACHECCR5BCHE | |
| SCHEMBL25625082 | 0.78 | IKZF1 (0.43) | IKZF1DRD2MEN1KMT2ACCR5 | |
| SCHEMBL25624857 | 0.77 | IKZF2 (0.42) | IKZF1DRD2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183782-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DI ONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2023-05-24 | — | — | EP | disclosed |