Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.33 |
| ▸ | SDCBP | O00560 | 1/20 | 0.33 |
| ▸ | SDC2 | P34741 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25626791 | 0.85 | DRD2 (0.42) | THRBLMNAALOX15MAPTIKZF1 | |
| SCHEMBL24790789 | 0.84 | IKZF2 (0.35) | THRBLMNAGAAKDM4EALOX15 | |
| SCHEMBL24891481 | 0.79 | NAMPT (0.36) | THRBLMNAGAAKDM4EALOX15 | |
| SCHEMBL25624328 | 0.77 | THRB (0.35) | THRBLMNAGAAIKZF1IKZF2 | |
| SCHEMBL24320367 | 0.76 | IKZF1 (0.40) | IKZF1IKZF2 | |
| SCHEMBL24891345 | 0.75 | THRB (0.34) | THRBLMNAGAAKDM4EALOX15 | |
| SCHEMBL24790237 | 0.75 | HRH3 (0.37) | DRD2DRD4DRD3 | |
| SCHEMBL24421543 | 0.73 | SDCBP (0.50) | THRBLMNAGAAKDM4EALOX15 | |
| SCHEMBL24421564 | 0.73 | SDCBP (0.42) | THRBLMNAKDM4EALOX15MAPT | |
| SCHEMBL25626312 | 0.73 | MAPT (0.36) | THRBGAAKDM4EALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183782-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DI ONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2023-05-24 | — | — | EP | disclosed |