Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17099954 | 0.98 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| Cyanamide SCHEMBL8891222 | 0.94 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL11038788 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL11400513 | 0.86 | LMNA (0.46) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL8636889 | 0.79 | LMNA (0.53) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL4556754 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAMAPTL3MBTL1 | |
| SCHEMBL17099951 | 0.79 | MEN1 (0.50) | ALDH1A1LMNAKMT2AMEN1CES2 | |
| SCHEMBL20524425 | 0.79 | OGG1 (0.55) | ALDH1A1KDM4EMAPTL3MBTL1KMT2A | |
| SCHEMBL4628703 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL262369 | 0.78 | ALOX15 (0.54) | ALDH1A1KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601232-B1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES | CURZA GLOBAL LLC (US) | 2022-11-23 | — | — | EP | disclosed |
| US-20220274949-A1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES | CURZA GLOBAL, LLC (US) | 2022-09-01 | — | — | US | disclosed |
| US-11339140-B2 | Compositions and methods comprising substituted 2-aminoimidazoles | CURZA GLOBAL, LLC (US) | 2022-05-24 | — | — | US | disclosed |
| US-11339140-B2 | Compositions and methods comprising substituted 2-aminoimidazoles | CURZA GLOBAL, LLC (US) | 2022-05-24 | — | — | US | disclosed |
| EP-3601232-A1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES | Curza Global LLC (US) | 2020-02-05 | — | — | EP | disclosed |
| US-10493061-B2 | Compositions and methods comprising 2-(acylamino)imidazoles | CURZA GLOBAL, LLC (US) | 2019-12-03 | — | — | US | disclosed |
| WO-2018184019-A1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES | CURZA GLOBAL, LLC (US) | 2018-10-04 | — | — | WO | disclosed |
| US-20170100375-A1 | COMPOSITIONS AND METHODS COMPRISING 2-(ACYLAMINO)IMIDAZOLES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-13 | — | — | US | disclosed |
| US-20170100375-A1 | COMPOSITIONS AND METHODS COMPRISING 2-(ACYLAMINO)IMIDAZOLES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-13 | — | — | US | disclosed |
| EP-3119394-A2 | COMPOSITIONS AND METHODS COMPRISING 2-(ACYLAMINO)IMIDAZOLES | Curza Global LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| WO-2002100826-A2 | SUBSTITUTED 3-ARYL-5-ARYL-[1,2,4]-OXADIAZOLES AND ANALOGS | CYTOVIA, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-0922086-B1 | BLEACHING AGENT COMPOSITIONS | JOHNSON CO LTD (JP) | 2002-10-30 | — | — | EP | disclosed |
| US-6159391-A | Bleaching agent compositions | S. C. JOHNSON & SON, INC. (US) | 2000-12-12 | — | — | US | disclosed |
| US-5929013-A | AQUEOUS MIXTURE CONTAINING HYDROGEN PEROXIDE OR PRECURSOR, CYANOUREA AND AN ALKALINE AGENT; NO GENERATION OF ODOR; BLEACHING MOLD ON WALLS AND FURNITURE | JOHNSON COMPANY LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0922086-A2 | BLEACHING AGENT COMPOSITIONS | Johnson Company, Ltd. (JP) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007815-A2 | BLEACHING AGENT COMPOSITIONS | JOHNSON COMPANY, LTD. (JP) | 1998-02-26 | — | — | WO | disclosed |
| WO-1998007826-A2 | BLEACHING AGENT COMPOSITIONS | JOHNSON COMPANY, LTD. (JP) | 1998-02-26 | — | — | WO | disclosed |
| EP-0813587-A1 | BLEACH PRODUCT | Johnson Company, Ltd. (JP) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996028533-A1 | BLEACH PRODUCT | JOHNSON CO., LTD. (JP) | 1996-09-19 | — | — | WO | disclosed |
| US-4088629-A | ADDING A PIPERIDINYL-GUANIDINE | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10493061-B2 | Compositions and methods comprising 2-(acylamino)imidazoles | AADAC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDAC6 | ALDH1A1 1008/4885KDM4E 470/4885LMNA 2597/4885 |
| US-20170100375-A1 | COMPOSITIONS AND METHODS COMPRISING 2-(ACYLAMINO)IMIDAZOLES | AADAC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HDAC6 | ALDH1A1 1008/4885KDM4E 470/4885LMNA 2597/4885 |
| US-20220274949-A1 | COMPOSITIONS AND METHODS COMPRISING SUBSTITUTED 2-AMINOIMIDAZOLES | AADAC, PAICS, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALDH1A1 1217/4885KDM4E 371/4885LMNA 2193/4885 |
| US-11339140-B2 | Compositions and methods comprising substituted 2-aminoimidazoles | AADAC, PAICS, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALDH1A1 1217/4885KDM4E 371/4885LMNA 2193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.