SCHEMBL7222773

SCHEMBL7222773

CC(C)CCCCOC(=O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.41
LMNA P02545 1/20 0.39
BLM P54132 1/20 0.38
PTPN1 P18031 1/20 0.35
CA1 P00915 3/20 0.34
NAAA Q02083 1/20 0.34
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
KDM4C Q9H3R0 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
KDM4A O75164 1/20 0.34
PHF8 Q9UPP1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HRH3 Q9Y5N1 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7224595 0.98 RARB (0.40) RARBLMNABLMNAAAKDM4C
SCHEMBL6477990 0.98 RARB (0.40) RARBLMNABLMNAAAKDM4C
SCHEMBL7224844 0.98 RARB (0.40) RARBLMNABLMNAAAKDM4C
SCHEMBL7219284 0.98 RARB (0.40) RARBLMNABLMNAAAKDM4C
SCHEMBL9278406 0.98 RARB (0.40) RARBLMNABLMNAAAKDM4C
SCHEMBL4675873 0.93 BLM (0.39) RARBLMNABLMPTPN1CA1
SCHEMBL30849949 0.90 LMNA (0.52) RARBLMNABLMPTPN1NAAA
SCHEMBL6476866 0.90 LMNA (0.52) RARBLMNABLMPTPN1NAAA
SCHEMBL6477852 0.90 LMNA (0.52) RARBLMNABLMPTPN1NAAA
SCHEMBL6472477 0.87 FAAH (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3839028-B1 CLEANING PRODUCT PROCTER & GAMBLE (US) 2025-01-15 EP disclosed
US-20240239786-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER YALE UNIVERSITY 2024-07-18 US disclosed
EP-4386075-A2 CLEANING PRODUCT The Procter & Gamble Company (US) 2024-06-19 EP disclosed
US-11911751-B2 Catalyst compositions for hydroformylation and methods of use thereof BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2024-02-27 US disclosed
US-11873312-B2 Transcriptome in vivo analysis (TIVA) and transcriptome in situ analysis (TISA) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-01-16 US disclosed
US-11834629-B2 Cleaning product THE PROCTER & GAMBLE COMPANY (US) 2023-12-05 US disclosed
US-11834627-B2 Cleaning product THE PROCTER & GAMBLE COMPANY (US) 2023-12-05 US disclosed
EP-4124651-B1 CLEANING PRODUCT PROCTER & GAMBLE (US) 2023-11-29 EP disclosed
US-11787794-B2 Aminothiazole compounds and methods using same TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2023-10-17 US disclosed
US-11753604-B2 Cleaning product THE PROCTER & GAMBLE COMPANY (US) 2023-09-12 US disclosed
US-20120283296-A1 PYRROLOPYRAZOLES FOR TREATING CNS DISORDERS AFRAXIS, INC. (US) 2012-11-08 US disclosed
US-20120270866-A1 8-ETHYL-6-(ARYL)PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONES FOR THE TREATMENT OF CNS DISORDERS AFRAXIS INC. (US) 2012-10-25 US disclosed
US-20120184547-A1 METHODS FOR TREATING SCHIZOPHRENIA AFRAXIS, INC. (US) 2012-07-19 US disclosed
US-20120157399-A1 BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF OBESITY AND DIABETES SATIOGEN PHARMACEUTICALS, INC. (US) 2012-06-21 US disclosed
US-20120046283-A1 COMPOUNDS FOR TREATING NEUROPSYCHIATRIC CONDITIONS AFRAXIS INC. (US) 2012-02-23 US disclosed
US-20120028981-A1 Kinase Knockdown Via Electrophilically Enhanced Inhibitors PRINCIPIA BIOPHARMA INC. (US) 2012-02-02 US disclosed
US-20110294833-A1 Methods for Healthy Aging SCRIPPS HEALTH (US) 2011-12-01 US disclosed
US-20110218210-A1 COMPOUNDS FOR TREATING ABNORMAL CELLULAR PROLIFERATION Taiga Biotechnologies (US) 2011-09-08 US disclosed
US-6667285-B1 Branched-chain carboxylic acid monoalkyl ester with outstanding hydrolytic stability NEW JAPAN CHEMICAL CO., LTD. (JP) 2003-12-23 US disclosed
EP-1225213-A1 LUBRICATING OIL FOR REFRIGERATOR, HYDRAULIC FLUID COMPOSITION FOR REFRIGERATOR AND METHOD FOR LUBRICATION OF REFRIGERATOR NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110218210-A1 COMPOUNDS FOR TREATING ABNORMAL CELLULAR PROLIFERATION MKI67, PCNA, CCNC RARB 819/4885LMNA 1353/4885BLM 1065/4885
US-11787794-B2 Aminothiazole compounds and methods using same BRCA1, ALDH7A1, MGMT RARB 3466/4885LMNA 3056/4885BLM 1796/4885
US-20120028981-A1 Kinase Knockdown Via Electrophilically Enhanced Inhibitors MAP3K20, MAP3K6, MAP3K19 RARB 2979/4885LMNA 3613/4885BLM 2706/4885
US-20120157399-A1 BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF OBESITY AND DIABETES SLC10A1, SLC10A2, ABCB11 RARB 504/4885LMNA 4642/4885BLM 3365/4885
US-11873312-B2 Transcriptome in vivo analysis (TIVA) and transcriptome in situ analysis (TISA) RNMT, RNGTT, NSUN2 RARB 270/4885LMNA 1554/4885BLM 1675/4885
US-20110294833-A1 Methods for Healthy Aging HTT, TELO2, GLA RARB 3716/4885LMNA 495/4885BLM 2567/4885
US-20120270866-A1 8-ETHYL-6-(ARYL)PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONES FOR THE TREATMENT OF CNS DISORDERS PAK2, PAK6, PAK5 RARB 3432/4885LMNA 4236/4885BLM 3249/4885
US-20120283296-A1 PYRROLOPYRAZOLES FOR TREATING CNS DISORDERS PAK2, PAK3, PAK5 RARB 3843/4885LMNA 4348/4885BLM 4461/4885
US-20240239786-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER BRCA1, RAD51, PARP3 RARB 737/4885LMNA 678/4885BLM 19/4885
US-20120046283-A1 COMPOUNDS FOR TREATING NEUROPSYCHIATRIC CONDITIONS PAK2, PAK5, PAK6 RARB 2702/4885LMNA 4498/4885BLM 3524/4885
US-20120184547-A1 METHODS FOR TREATING SCHIZOPHRENIA PAK2, PAK3, PAK4 RARB 937/4885LMNA 4009/4885BLM 4601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.