SCHEMBL2479673

SCHEMBL2479673

Cc1cnc(-c2ccccc2)c(C)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
RAB9A P51151 2/20 0.46
MAPT P10636 2/20 0.46
POLB P06746 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 1/20 0.46
PKM P14618 1/20 0.46
KMT2A Q03164 1/20 0.46
CKS1B P61024 1/20 0.44
SKP1 P63208 1/20 0.44
SKP2 Q13309 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
PDE10A Q9Y233 1/20 0.41
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
NPC1 O15118 1/20 0.39
PDGFRB P09619 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15695138 0.88 KDM4E (0.41) KDM4ERAB9AMAPTPOLBALDH1A1
SCHEMBL13299566 0.80 MAPK14 (0.46) RAB9ASMN1; SMN2HPGDNPC1MAPK14
SCHEMBL9748838 0.79 MAPK14 (0.46) CCR1CCR5CCR8PTGS2MAPK13
SCHEMBL10205837 0.77 NFKB1 (0.46) KDM4ERAB9AMAPTPOLBALDH1A1
SCHEMBL2481047 0.77 ADORA2A (0.47) KDM4ERAB9AMAPTPOLBALDH1A1
SCHEMBL18729644 0.77 NPC1 (0.41) KDM4ERAB9AMAPTALDH1A1MEN1
SCHEMBL19537684 0.75 ADORA2A (0.54) KDM4ERAB9AMAPTPOLBALDH1A1
SCHEMBL2482626 0.74 KDM4E (0.50) KDM4ERAB9AMAPTPOLBALDH1A1
SCHEMBL29342351 0.74 CCR1 (0.59) KDM4ERAB9AMAPTPOLBALDH1A1
SCHEMBL31199032 0.74 KDM4E (0.55) KDM4ERAB9AMAPTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 US disclosed
CN-115322227-B Divalent platinum or palladium metal complex phosphorescent materials and devices based on coordination of 8-phenylquinoline and derivatives thereof 浙江工业大学 2024-02-02 CN disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
US-11825734-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-21 US disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-11818946-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 US disclosed
US-11812622-B2 Organic electroluminescent compounds and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-07 US disclosed
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20110060143-A1 Stable and Efficient Electroluminescent Materials KWONG RAYMOND 2011-03-10 US disclosed
US-7851072-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2010-12-14 US disclosed
CN-101076902-B Stable and effective electroluminescent material UNIVERSAL DISPLAY CORP 2010-07-28 CN disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
US-20100141127-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-06-10 US disclosed
WO-2010056669-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2010-05-20 WO disclosed
CN-101076902-A Stable and effective electroluminescent material UNIVERSAL DISPLAY CORP (US) 2007-11-21 CN disclosed
EP-1763902-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2007-03-21 EP disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
WO-2006014599-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100141127-A1 PHOSPHORESCENT EMITTERS PAICS, TYMP, NUDT1 KDM4E 2674/4885RAB9A 2958/4885MAPT 106/4885
US-11825734-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP KDM4E 3905/4885RAB9A 1234/4885MAPT 2251/4885
US-11818946-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, AOC3 KDM4E 3165/4885RAB9A 1920/4885MAPT 2857/4885
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, LDLR KDM4E 2019/4885RAB9A 1869/4885MAPT 3591/4885
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 KDM4E 3068/4885RAB9A 1474/4885MAPT 2644/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDM4E 4507/4885RAB9A 2081/4885MAPT 2502/4885
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR KDM4E 1316/4885RAB9A 812/4885MAPT 4481/4885
US-20110060143-A1 Stable and Efficient Electroluminescent Materials EML4, ITGA5, CHRM5 KDM4E 976/4885RAB9A 1523/4885MAPT 2019/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR KDM4E 1788/4885RAB9A 2009/4885MAPT 4002/4885
US-11832507-B2 Organic electroluminescent materials and devices MLX, LBR, LDLR KDM4E 2019/4885RAB9A 1869/4885MAPT 3591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.