⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24394125 | 0.88 | ALDH1A1 (0.30) | — | |
| SCHEMBL24394132 | 0.86 | L3MBTL1 (0.33) | — | |
| SCHEMBL24801652 | 0.85 | GRM4 (0.31) | — | |
| SCHEMBL24394129 | 0.83 | PTGDR (0.31) | — | |
| SCHEMBL24394237 | 0.81 | FABP4 (0.32) | — | |
| SCHEMBL24394133 | 0.81 | — | — | |
| SCHEMBL24394126 | 0.79 | — | — | |
| SCHEMBL26941602 | 0.77 | DRD2 (0.31) | — | |
| SCHEMBL24802222 | 0.77 | FABP5 (0.40) | — | |
| SCHEMBL30304227 | 0.77 | FABP5 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240335451-A1 | ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | SITRYX THERAPEUTICS LIMITED (GB) | 2024-10-10 | — | — | US | claimed |
| EP-4359390-A1 | ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | Sitryx Therapeutics Limited (GB) | 2024-05-01 | — | — | EP | claimed |
| WO-2022269251-A1 | ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-12-29 | — | — | WO | claimed |
| US-20240335451-A1 | ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | SITRYX THERAPEUTICS LIMITED (GB) | 2024-10-10 | — | — | US | disclosed |
| EP-4359390-A1 | ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | Sitryx Therapeutics Limited (GB) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022269251-A1 | ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022269251-A1 | ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-12-29 | — | — | WO | disclosed |