SCHEMBL4026544

SCHEMBL4026544

Fc1cccc(-c2ccccn2)c1.Fc1cccc(-c2ccccn2)c1.Fc1cccc(-c2ccccn2)c1.[Ir]

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 4/20 0.60
BCHE P06276 1/20 0.51
ACHE P22303 1/20 0.51
DCTPP1 Q9H773 1/20 0.51
TLR4 O00206 1/20 0.49
TLR2 O60603 1/20 0.49
CYP2A6 P11509 1/20 0.48
KDM4E B2RXH2 3/20 0.48
LMNA P02545 2/20 0.48
CCR1 P32246 2/20 0.48
CCR5 P51681 2/20 0.48
CCR8 P51685 2/20 0.48
CYP1A2 P05177 1/20 0.48
POLB P06746 1/20 0.48
METAP1 P53582 1/20 0.48
BLM P54132 1/20 0.48
HIF1A Q16665 1/20 0.48
DOHH Q9BU89 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
KMO O15229 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29883580 0.98 GRM5 (0.62) GRM5BCHEACHEDCTPP1TLR4
SCHEMBL3233604 0.98 GRM5 (0.62) GRM5BCHEACHEDCTPP1TLR4
SCHEMBL3767444 0.96 GRM5 (0.57) GRM5BCHEACHEDCTPP1TLR4
SCHEMBL29398603 0.94 GRM5 (0.59) GRM5BCHEACHEDCTPP1TLR4
SCHEMBL2480128 0.94 GRM5 (0.59) GRM5BCHEACHEDCTPP1TLR4
SCHEMBL9905077 0.84 GRM5 (0.56) GRM5BCHEACHEDCTPP1KDM4E
SCHEMBL502867 0.83 KDM4E (0.62) GRM5TLR4TLR2CYP2A6KDM4E
SCHEMBL29679578 0.83 KDM4E (0.62) GRM5TLR4TLR2CYP2A6KDM4E
SCHEMBL3779014 0.82 GRM5 (0.59) GRM5DCTPP1TLR4TLR2CYP2A6
SCHEMBL3773686 0.82 GRM5 (0.47) GRM5DCTPP1CYP2A6METAP1CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1598879-B1 LUMINESCENCE DEVICE, DISPLAY APPARATUS AND METAL COORDINATION COMPOUND CANON KK (JP) 2015-12-02 EP disclosed
US-7534506-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7026062-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2006-04-11 US disclosed
EP-1191613-B1 Luminescence device, display apparatus and metal coordination compound CANON KK (JP) 2006-03-29 EP disclosed
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2006-01-19 US disclosed
EP-1598879-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-11-23 EP disclosed
US-20050014025-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-01-20 US disclosed
US-6815091-B2 IRIDIUM, RHODIUM, OR PALLADIUM-PHENYLPYRIDINE COMPLEX WITH SPECIFIED SUBSTITUENT(S); HIGH-EFFICIENCY LUMINESCENCE, HIGH BRIGHTNESS FOR A LONG TIME WHILE MINIMIZING DETERIORATION IN LUMINESCENCE IN ENERGIZED STATE CANON KABUSHIKI KAISHA (JP) 2004-11-09 US disclosed
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1191613-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound SOD1, ICOSLG, CCRL2 GRM5 2488/4885BCHE 1866/4885ACHE 605/4885
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CDYL, ZC3HAV1L, ICOSLG GRM5 1723/4885BCHE 617/4885ACHE 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.