SCHEMBL3233604

SCHEMBL3233604

Fc1cccc(-c2ccccn2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 4/20 0.62
BCHE P06276 1/20 0.53
ACHE P22303 1/20 0.53
DCTPP1 Q9H773 1/20 0.52
KDM4E B2RXH2 3/20 0.50
LMNA P02545 2/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
CYP2A6 P11509 1/20 0.50
TLR4 O00206 1/20 0.50
TLR2 O60603 1/20 0.50
KMO O15229 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29883580 1.00 GRM5 (0.62) GRM5BCHEACHEDCTPP1KDM4E
SCHEMBL4026544 0.98 GRM5 (0.60) GRM5BCHEACHEDCTPP1KDM4E
SCHEMBL2480128 0.96 GRM5 (0.59) GRM5BCHEACHEDCTPP1KDM4E
SCHEMBL29398603 0.96 GRM5 (0.59) GRM5BCHEACHEDCTPP1KDM4E
SCHEMBL3767444 0.94 GRM5 (0.57) GRM5BCHEACHEDCTPP1KDM4E
SCHEMBL9905077 0.85 GRM5 (0.56) GRM5BCHEACHEDCTPP1KDM4E
SCHEMBL502867 0.85 KDM4E (0.62) GRM5KDM4ELMNACCR1CCR5
SCHEMBL29679578 0.85 KDM4E (0.62) GRM5KDM4ELMNACCR1CCR5
SCHEMBL5846133 0.83 GRM5 (0.60) GRM5KDM4ELMNACCR1CCR5
SCHEMBL5945969 0.83 GRM5 (0.56) GRM5KDM4ELMNACCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011162562-A2 [6+5] FUSED BICYCLES AS A THROMBIN ANTAGONIST, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE BICYCLES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2011-12-29 WO claimed
US-12559671-B2 Light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2026-02-24 US disclosed
CN-118290328-A Hydrocarbon pyridine and preparation method thereof 北京师范大学 2024-07-05 CN disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
EP-1191613-B1 Luminescence device, display apparatus and metal coordination compound CANON KK (JP) 2006-03-29 EP disclosed
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2006-01-19 US disclosed
EP-1598879-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-11-23 EP disclosed
CN-1694700-A Non-nucleoside reverse transcriptase inhibitors MEDIVIR AB (SE) 2005-11-09 CN disclosed
US-20050014025-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-01-20 US disclosed
US-6815091-B2 IRIDIUM, RHODIUM, OR PALLADIUM-PHENYLPYRIDINE COMPLEX WITH SPECIFIED SUBSTITUENT(S); HIGH-EFFICIENCY LUMINESCENCE, HIGH BRIGHTNESS FOR A LONG TIME WHILE MINIMIZING DETERIORATION IN LUMINESCENCE IN ENERGIZED STATE CANON KABUSHIKI KAISHA (JP) 2004-11-09 US disclosed
US-20030040627-A1 Luminescent organometallic compound and light emitting device SANYO ELECTRIC CO., LTD. (JP) 2003-02-27 US disclosed
CN-1397559-A Luminous organic intermetallic compound and luminous element SANYO ELECTRIC CO (JP) 2003-02-19 CN disclosed
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1191613-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, OXER1, LBR GRM5 855/4885BCHE 1740/4885ACHE 1262/4885
US-20030040627-A1 Luminescent organometallic compound and light emitting device IK, CRY1, LBR GRM5 1398/4885BCHE 2140/4885ACHE 1029/4885
US-12559671-B2 Light-emitting device SCO2, GRIN2C, GLRA2 GRM5 20/4885BCHE 2805/4885ACHE 2822/4885
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, OXSR1 GRM5 2265/4885BCHE 2489/4885ACHE 1391/4885
US-20230348509-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, OCIAD1, LBR GRM5 2690/4885BCHE 1137/4885ACHE 1087/4885
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound SOD1, ICOSLG, CCRL2 GRM5 2488/4885BCHE 1866/4885ACHE 605/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 GRM5 1737/4885BCHE 3757/4885ACHE 2296/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 GRM5 2354/4885BCHE 2120/4885ACHE 1307/4885
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CDYL, ZC3HAV1L, ICOSLG GRM5 1723/4885BCHE 617/4885ACHE 1228/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 GRM5 3314/4885BCHE 4222/4885ACHE 2561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.