Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 11/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397909 | 0.90 | HDAC1 (0.40) | HDAC1HDAC3HDAC2HDAC6PDE2A | |
| SCHEMBL29601146 | 0.90 | HDAC1 (0.40) | HDAC1HDAC3HDAC2HDAC6PDE2A | |
| SCHEMBL24801647 | 0.87 | HDAC1 (0.38) | HDAC1HDAC3HDAC2HDAC6PDE2A | |
| SCHEMBL24802238 | 0.83 | SLC6A3 (0.38) | HDAC1HDAC3HDAC2HDAC6PDE2A | |
| SCHEMBL25043232 | 0.81 | HDAC1 (0.40) | HDAC1HDAC3HDAC2HDAC6PDE2A | |
| SCHEMBL29601371 | 0.78 | SLC6A2 (0.36) | TRPV1 | |
| SCHEMBL24397807 | 0.78 | SLC6A2 (0.36) | TRPV1 | |
| SCHEMBL24398054 | 0.75 | — | — | |
| SCHEMBL24394121 | 0.74 | LMNA (0.33) | — | |
| SCHEMBL24801183 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022269251-A1 | ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-12-29 | — | — | WO | disclosed |