Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397807 | 1.00 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3MRGPRX4NOTUM | |
| SCHEMBL24394121 | 0.89 | LMNA (0.33) | SLC6A2SLC6A4SLC6A3MRGPRX4NOTUM | |
| SCHEMBL24397909 | 0.88 | HDAC1 (0.40) | TRPV1 | |
| SCHEMBL29601146 | 0.88 | HDAC1 (0.40) | TRPV1 | |
| SCHEMBL24397839 | 0.84 | MAPT (0.38) | SLC6A4SLC6A3OPRM1HTTMAPT | |
| SCHEMBL24394104 | 0.82 | THRB (0.37) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL24397743 | 0.80 | DRD2 (0.39) | LMNAMAPT | |
| SCHEMBL24397872 | 0.79 | SLC6A3 (0.39) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL24397786 | 0.79 | APP (0.38) | SLC6A4SLC6A3KCNH2PPARD | |
| SCHEMBL24398059 | 0.78 | SLC6A3 (0.41) | SLC6A2SLC6A4SLC6A3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237404-A1 | NOVEL COMPOUNDS | Sitryx Therapeutics Limited (GB) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022090724-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |